Characterization of the effector cells in Con A-induced cytotoxicity against HEp 2 tumour targets.

E. Pócsik, R. González-Cabello, K. Benedek, A. Perl, I. Láng, P. Gergely

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Abstract

Con A-induced cytotoxic activity of human lymphocyte subpopulations obtained by cell fractionation procedures was studied in a test system using human epipharynx carcinoma cells (HEp 2) as targets. Only T lymphocytes were cytotoxic, non-T cells exerted no cytotoxic activity, but enhanced the adherence of the tumour cells. Tnon-G lymphocytes (Fc-receptor negative T cells) were more active than TG cells (Fc-receptor-positive T cells) in mediating the Con A-induced cytotoxic reaction.

Original languageEnglish
Pages (from-to)41-46
Number of pages6
JournalActa medica Hungarica
Volume40
Issue number1
Publication statusPublished - Dec 1 1983

ASJC Scopus subject areas

  • Medicine(all)

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    Pócsik, E., González-Cabello, R., Benedek, K., Perl, A., Láng, I., & Gergely, P. (1983). Characterization of the effector cells in Con A-induced cytotoxicity against HEp 2 tumour targets. Acta medica Hungarica, 40(1), 41-46.