Characterization of the branching structure of the lung from "macroscopic" pressure-volume measurements

A. Majumdar, A. M. Alencar, S. V. Buldyrev, Z. Hantos, H. E. Stanley, B. Suki

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We analyze the problem of fluid flow in a bifurcating structure containing random blockages that can be removed by fluid pressure. We introduce an asymmetric tree model and find that the predicted pressure-volume relation is connected to the distribution Pi(n) of the generation number n of the tree's terminal segments. We use this relation to explore the branching structure of the lung by analyzing experimental pressure-volume data from dog lungs. The Pi(n) extracted from the data using the model agrees well with experimental data on the branching structure. We can thus obtain information about the asymmetric structure of the lung from macroscopic, noninvasive pressure-volume measurements.

Original languageEnglish
Pages (from-to)58102
Number of pages1
JournalPhysical Review Letters
Volume87
Issue number5
Publication statusPublished - Jul 30 2001

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lungs
Pressure
Lung
dogs
fluid pressure
fluid flow
Dogs

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Majumdar, A., Alencar, A. M., Buldyrev, S. V., Hantos, Z., Stanley, H. E., & Suki, B. (2001). Characterization of the branching structure of the lung from "macroscopic" pressure-volume measurements. Physical Review Letters, 87(5), 58102.

Characterization of the branching structure of the lung from "macroscopic" pressure-volume measurements. / Majumdar, A.; Alencar, A. M.; Buldyrev, S. V.; Hantos, Z.; Stanley, H. E.; Suki, B.

In: Physical Review Letters, Vol. 87, No. 5, 30.07.2001, p. 58102.

Research output: Contribution to journalArticle

Majumdar, A, Alencar, AM, Buldyrev, SV, Hantos, Z, Stanley, HE & Suki, B 2001, 'Characterization of the branching structure of the lung from "macroscopic" pressure-volume measurements', Physical Review Letters, vol. 87, no. 5, pp. 58102.
Majumdar, A. ; Alencar, A. M. ; Buldyrev, S. V. ; Hantos, Z. ; Stanley, H. E. ; Suki, B. / Characterization of the branching structure of the lung from "macroscopic" pressure-volume measurements. In: Physical Review Letters. 2001 ; Vol. 87, No. 5. pp. 58102.
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