Characterization of responses to enkephalins and FMRFamide on B neurons of the cerebral ganglion of Aplysia

K. S. -Rozsa, G. Stefano, J. Salánki, D. O. Carpenter

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

1. Cerebral B neurons of Aplysia vary in reponse to leu- and met-enkephalin. Some neurons show inward currents to the enkephalins, while others show outward or biphasic currents. 2. The FMRFamide and acetylcholine responses also vary among the B neurons. 3. While acetylcholine and FMRFamide responses were usually accompanied by clear conductance changes and voltage dependency, those to the enkephalins often showed no conductance change and minimal voltage dependency. 4. The inward currents elicited by both the enkephalins and FMRFamide were increased by forskolin, an activator of adenylate cyclase, and by phosphodiesterase inhibitors.

Original languageEnglish
Pages (from-to)403-412
Number of pages10
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume99
Issue number3
DOIs
Publication statusPublished - 1991

Fingerprint

FMRFamide
Aplysia
Enkephalins
Ganglia
Neurons
Acetylcholine
Leucine Enkephalin
Methionine Enkephalin
Phosphodiesterase Inhibitors
Colforsin

ASJC Scopus subject areas

  • Pharmacology
  • Immunology

Cite this

Characterization of responses to enkephalins and FMRFamide on B neurons of the cerebral ganglion of Aplysia. / -Rozsa, K. S.; Stefano, G.; Salánki, J.; Carpenter, D. O.

In: Comparative Biochemistry and Physiology. Part C, Comparative, Vol. 99, No. 3, 1991, p. 403-412.

Research output: Contribution to journalArticle

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