Characterization of left atrial dysfunction in hypereosinophilic syndrome - Insights from the Motion analysis of the heart and great vessels by three-dimensional speckle tracking echocardiography in pathological cases (MAGYAR-Path) Study

Attila Nemes, Imelda Marton, Péter Domsik, Anita Kalapos, Éva Pósfai, S. Modok, Zita Borbényi, T. Forster

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction: The present study was designed to compare three-dimensional speckle tracking echocardiography (3DSTE)-derived left atrial (LA) volumetric, volume-based functional and strain parameters between patients with hypereosinophilic syndrome (HES) and matched controls. Methods: A total of 10 HES patients and 19 age- and gender-matched healthy controls were included in the study. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all HES cases and controls. Results: Significantly increased maximum (72.9±38.8 ml vs. 45.6±15.5 ml, p=0.01) and minimum (46.3±33.3 ml vs. 26.0±15.0 ml, p=0.03) LA volumes and LA volume before atrial contraction (62.0±36.0 ml vs. 36.5±16.6 ml, p=0.01) were found in HES patients compared to controls. Both peak global (18.3±6.7% vs. 25.6±9.0%, p=0.03) and mean segmental (22.2±6.0% vs. 31.0±12.1%, p=0.04) circumferential strains were significantly reduced in HES patients, suggesting decreased LA reservoir function. Conclusion: Increased LA volumes can be demonstrated in HES patients, accompanied by reduced LA peak circumferential strain as assessed by 3DSTE, suggesting LA remodeling.

Original languageEnglish
JournalRevista Portuguesa de Cardiologia
DOIs
Publication statusAccepted/In press - Aug 9 2015

Fingerprint

Hypereosinophilic Syndrome
Echocardiography
Left Atrial Function
Atrial Remodeling
Doppler Echocardiography

Keywords

  • Echocardiography
  • Function
  • Left atrium
  • Speckle tracking
  • Three-dimensional
  • Two-dimensional

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

@article{82e1c68aa8f44b76bc9cf91208b19b2a,
title = "Characterization of left atrial dysfunction in hypereosinophilic syndrome - Insights from the Motion analysis of the heart and great vessels by three-dimensional speckle tracking echocardiography in pathological cases (MAGYAR-Path) Study",
abstract = "Introduction: The present study was designed to compare three-dimensional speckle tracking echocardiography (3DSTE)-derived left atrial (LA) volumetric, volume-based functional and strain parameters between patients with hypereosinophilic syndrome (HES) and matched controls. Methods: A total of 10 HES patients and 19 age- and gender-matched healthy controls were included in the study. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all HES cases and controls. Results: Significantly increased maximum (72.9±38.8 ml vs. 45.6±15.5 ml, p=0.01) and minimum (46.3±33.3 ml vs. 26.0±15.0 ml, p=0.03) LA volumes and LA volume before atrial contraction (62.0±36.0 ml vs. 36.5±16.6 ml, p=0.01) were found in HES patients compared to controls. Both peak global (18.3±6.7{\%} vs. 25.6±9.0{\%}, p=0.03) and mean segmental (22.2±6.0{\%} vs. 31.0±12.1{\%}, p=0.04) circumferential strains were significantly reduced in HES patients, suggesting decreased LA reservoir function. Conclusion: Increased LA volumes can be demonstrated in HES patients, accompanied by reduced LA peak circumferential strain as assessed by 3DSTE, suggesting LA remodeling.",
keywords = "Echocardiography, Function, Left atrium, Speckle tracking, Three-dimensional, Two-dimensional",
author = "Attila Nemes and Imelda Marton and P{\'e}ter Domsik and Anita Kalapos and {\'E}va P{\'o}sfai and S. Modok and Zita Borb{\'e}nyi and T. Forster",
year = "2015",
month = "8",
day = "9",
doi = "10.1016/j.repc.2015.11.017",
language = "English",
journal = "Revista Portuguesa de Cardiologia",
issn = "0870-2551",
publisher = "Sociedade Portuguesa De Cardiologia",

}

TY - JOUR

T1 - Characterization of left atrial dysfunction in hypereosinophilic syndrome - Insights from the Motion analysis of the heart and great vessels by three-dimensional speckle tracking echocardiography in pathological cases (MAGYAR-Path) Study

AU - Nemes, Attila

AU - Marton, Imelda

AU - Domsik, Péter

AU - Kalapos, Anita

AU - Pósfai, Éva

AU - Modok, S.

AU - Borbényi, Zita

AU - Forster, T.

PY - 2015/8/9

Y1 - 2015/8/9

N2 - Introduction: The present study was designed to compare three-dimensional speckle tracking echocardiography (3DSTE)-derived left atrial (LA) volumetric, volume-based functional and strain parameters between patients with hypereosinophilic syndrome (HES) and matched controls. Methods: A total of 10 HES patients and 19 age- and gender-matched healthy controls were included in the study. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all HES cases and controls. Results: Significantly increased maximum (72.9±38.8 ml vs. 45.6±15.5 ml, p=0.01) and minimum (46.3±33.3 ml vs. 26.0±15.0 ml, p=0.03) LA volumes and LA volume before atrial contraction (62.0±36.0 ml vs. 36.5±16.6 ml, p=0.01) were found in HES patients compared to controls. Both peak global (18.3±6.7% vs. 25.6±9.0%, p=0.03) and mean segmental (22.2±6.0% vs. 31.0±12.1%, p=0.04) circumferential strains were significantly reduced in HES patients, suggesting decreased LA reservoir function. Conclusion: Increased LA volumes can be demonstrated in HES patients, accompanied by reduced LA peak circumferential strain as assessed by 3DSTE, suggesting LA remodeling.

AB - Introduction: The present study was designed to compare three-dimensional speckle tracking echocardiography (3DSTE)-derived left atrial (LA) volumetric, volume-based functional and strain parameters between patients with hypereosinophilic syndrome (HES) and matched controls. Methods: A total of 10 HES patients and 19 age- and gender-matched healthy controls were included in the study. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all HES cases and controls. Results: Significantly increased maximum (72.9±38.8 ml vs. 45.6±15.5 ml, p=0.01) and minimum (46.3±33.3 ml vs. 26.0±15.0 ml, p=0.03) LA volumes and LA volume before atrial contraction (62.0±36.0 ml vs. 36.5±16.6 ml, p=0.01) were found in HES patients compared to controls. Both peak global (18.3±6.7% vs. 25.6±9.0%, p=0.03) and mean segmental (22.2±6.0% vs. 31.0±12.1%, p=0.04) circumferential strains were significantly reduced in HES patients, suggesting decreased LA reservoir function. Conclusion: Increased LA volumes can be demonstrated in HES patients, accompanied by reduced LA peak circumferential strain as assessed by 3DSTE, suggesting LA remodeling.

KW - Echocardiography

KW - Function

KW - Left atrium

KW - Speckle tracking

KW - Three-dimensional

KW - Two-dimensional

UR - http://www.scopus.com/inward/record.url?scp=84964203137&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964203137&partnerID=8YFLogxK

U2 - 10.1016/j.repc.2015.11.017

DO - 10.1016/j.repc.2015.11.017

M3 - Article

C2 - 27118091

AN - SCOPUS:84964203137

JO - Revista Portuguesa de Cardiologia

JF - Revista Portuguesa de Cardiologia

SN - 0870-2551

ER -