Characterization of left atrial dysfunction in hypereosinophilic syndrome - Insights from the Motion analysis of the heart and great vessels by three-dimensional speckle tracking echocardiography in pathological cases (MAGYAR-Path) Study

Attila Nemes, Imelda Marton, Péter Domsik, Anita Kalapos, Éva Pósfai, Szabolcs Modok, Zita Borbényi, Tamás Forster

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction The present study was designed to compare three-dimensional speckle tracking echocardiography (3DSTE)-derived left atrial (LA) volumetric, volume-based functional and strain parameters between patients with hypereosinophilic syndrome (HES) and matched controls. Methods A total of 10 HES patients and 19 age- and gender-matched healthy controls were included in the study. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all HES cases and controls. Results Significantly increased maximum (72.9±38.8 ml vs. 45.6±15.5 ml, p=0.01) and minimum (46.3±33.3 ml vs. 26.0±15.0 ml, p=0.03) LA volumes and LA volume before atrial contraction (62.0±36.0 ml vs. 36.5±16.6 ml, p=0.01) were found in HES patients compared to controls. Both peak global (18.3±6.7% vs. 25.6±9.0%, p=0.03) and mean segmental (22.2±6.0% vs. 31.0±12.1%, p=0.04) circumferential strains were significantly reduced in HES patients, suggesting decreased LA reservoir function. Conclusion Increased LA volumes can be demonstrated in HES patients, accompanied by reduced LA peak circumferential strain as assessed by 3DSTE, suggesting LA remodeling.

Original languageEnglish
Pages (from-to)277-283
Number of pages7
JournalRevista Portuguesa de Cardiologia
Volume35
Issue number5
DOIs
Publication statusPublished - May 1 2016

Keywords

  • Echocardiography
  • Function
  • Left atrium
  • Speckle tracking
  • Three-dimensional
  • Two-dimensional

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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