The purpose of this study was to further characterize the altered metabolism spondylolisthesis that promotes disease progression. Degenerative human cartilage (intervertebral disc, facet joint and vertebral end-plate) was obtained during 15 posterior lumbar spine interbody fusion procedures performed at the University of Szeged. The thermal properties of samples were determined by differential scanning calorimetry (Mettler-Toledo DSC 821 e). Greatest change in the enthalpy was observed in the intervertebral disc samples: -1600.78 J g -1. Denaturation caused by heating in the normal human hyaline cartilage needed -1493.31 J g -1 energy. Characterization of the altered metabolism that promotes disease progression should lead to future treatment options.
- Human hyaline cartilage
ASJC Scopus subject areas
- Condensed Matter Physics
- Physical and Theoretical Chemistry