Characterization of bone forming cells in posttraumatic myositis ossificans by lectins

T. Illés, J. Dubousset, M. Szendröi, J. Fischer

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Lectins were used to characterize bone forming cells in posttraumatic myositis ossificans. The lectins applied were as follows: Aracbis bypogaea (PNA): specific for β-D-galactose (1,3)N-acetyl-D-galactosamin (Gal-1,3 GaINac), Canavalia ensiformis (Con A): specific for cc-D-glucose (D-Glc) and ct-D-mannose (D-Man) and Wheat germ (WGA): specific for N=acetyl(1,4)D-glucosamlne (Glc-NaQ and neuraminic acid. The development of myositis ossificans was characterized by the appearance ofa WGA binding cell population. The lectin-binding sites appeared as a cluster in the supranuclear cytoplasm, corresponding to the Golgi-complex. However, the FGA lectin-binding sites disappeared in the mature form of myositis ossificans. We assume that these lectin binding cells may be the bone marrow derived precursors of myofibroblast-like cells which are responsible for bone formation within the damaged muscle.

Original languageEnglish
Pages (from-to)172-176
Number of pages5
JournalPathology Research and Practice
Volume188
Issue number1-2
DOIs
Publication statusPublished - Jan 1 1992

Keywords

  • Bone forming cells
  • Myositis ossificons
  • WGA

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology

Fingerprint Dive into the research topics of 'Characterization of bone forming cells in posttraumatic myositis ossificans by lectins'. Together they form a unique fingerprint.

  • Cite this