Characterization of a submicro-X-ray fluorescence setup on the B16 beamline at Diamond Light Source

M. Rauwolf, A. Turyanskaya, D. Ingerle, N. Szoboszlai, I. Pape, A. W. Malandain, O. J.L. Fox, L. Hahn, K. J.S. Sawhney, C. Streli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An X-ray fluorescence setup has been tested on the B16 beamline at the Diamond Light Source synchrotron with two different excitation energies (12.7 and 17 keV). This setup allows the scanning of thin samples (thicknesses up to several micrometers) with a sub-micrometer resolution (beam size of 500 nm × 600 nm determined with a 50 µm Au wire). Sensitivities and detection limits reaching values of 249 counts s−1 fg−1 and 4 ag in 1000 s, respectively (for As Kα excited with 17 keV), are presented in order to demonstrate the capabilities of this setup. Sample measurements of a human bone and a single cell performed at B16 are presented in order to illustrate the suitability of the setup in biological applications.

Original languageEnglish
Pages (from-to)1189-1195
Number of pages7
JournalJournal of Synchrotron Radiation
Volume25
Issue number4
DOIs
Publication statusPublished - Jul 2018

Keywords

  • SR submicro-XRF
  • beamline B16
  • cells
  • elemental imaging
  • human bone
  • scanning

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Instrumentation

Fingerprint Dive into the research topics of 'Characterization of a submicro-X-ray fluorescence setup on the B16 beamline at Diamond Light Source'. Together they form a unique fingerprint.

  • Cite this

    Rauwolf, M., Turyanskaya, A., Ingerle, D., Szoboszlai, N., Pape, I., Malandain, A. W., Fox, O. J. L., Hahn, L., Sawhney, K. J. S., & Streli, C. (2018). Characterization of a submicro-X-ray fluorescence setup on the B16 beamline at Diamond Light Source. Journal of Synchrotron Radiation, 25(4), 1189-1195. https://doi.org/10.1107/S1600577518006203