Characteristics of hyperacute rejection of swine kidney xenografts perfused with canine blood

T. Tóth, E. Rőth, T. Szmolenszky, S. Pácsa, B. Török

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Twenty-five swine kidney xenografts previously flushed with Collins-4 solution were perfused with canine blood and the functional and morphological changes resulting from xenoperfusion were studied. Blood flow of the kidneys practically ceased by the end of 8 minutes parallel with progressive swelling and cyanosis of the organ. Microscopic study of the kidneys revealed gross destruction of the glomerular and tubular apparatus, marked by extensive oedema, interstitial haemorrhages, diffuse capillary thrombosis and damage to the cell membrane.

Original languageEnglish
Pages (from-to)323-329
Number of pages7
JournalInternational Urology and Nephrology
Volume8
Issue number4
DOIs
Publication statusPublished - Dec 1976

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Heterografts
Canidae
Swine
Kidney
Cyanosis
Edema
Thrombosis
Cell Membrane
Hemorrhage

ASJC Scopus subject areas

  • Urology
  • Nephrology
  • Geriatrics and Gerontology

Cite this

Characteristics of hyperacute rejection of swine kidney xenografts perfused with canine blood. / Tóth, T.; Rőth, E.; Szmolenszky, T.; Pácsa, S.; Török, B.

In: International Urology and Nephrology, Vol. 8, No. 4, 12.1976, p. 323-329.

Research output: Contribution to journalArticle

Tóth, T. ; Rőth, E. ; Szmolenszky, T. ; Pácsa, S. ; Török, B. / Characteristics of hyperacute rejection of swine kidney xenografts perfused with canine blood. In: International Urology and Nephrology. 1976 ; Vol. 8, No. 4. pp. 323-329.
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