A sejtes infiltráció jellemzése a kilöködö vesetransplantatumban.

Translated title of the contribution: Characteristics of cellular infiltration in rejected renal grafts

T. Nádasdy, T. Krenács, K. Kalmár-Nagy, E. Csajbók, K. Boda, J. Ormos

Research output: Contribution to journalReview article


The composition of the cellular infiltrate in 42 needle and wedge biopsies of transplanted kidneys was investigated immunohistochemically. The various inflammatory cell populations were examined in different rejection types and cyclosporin-A nephrotoxicity (CsAN) as well as in different locations in the graft (perivascular and intertubular area, tubular epithelium, glomeruli) separately. There was generally a Th cell predominance except the most unfavorable rejection type, the acute vascular rejection (AVR), where the Tc cells outnumbered all other infiltrating cell populations. The most macrophages too were detected in AVR. The high proportion of plasma cells in chronic rejection indicate an important role of the humoral immune response in this type of rejection, and could also be used as a differential diagnostic sign versus CsAN.

Original languageHungarian
Pages (from-to)189-193
Number of pages5
JournalOrvosi hetilap
Issue number4
Publication statusPublished - Jan 28 1990


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nádasdy, T., Krenács, T., Kalmár-Nagy, K., Csajbók, E., Boda, K., & Ormos, J. (1990). A sejtes infiltráció jellemzése a kilöködö vesetransplantatumban. Orvosi hetilap, 131(4), 189-193.