A human Fcγ-receptorok jellemzoi, szerepuk es klinikai jelentoseguk

Translated title of the contribution: Characteristics and the clinical role of human Fcγ receptors

Research output: Contribution to journalArticle

Abstract

Receptors for the Fc region of IgG (FcγR) provide a significant role in the specific and aspecific responses of the immune system. When FcγR interact with immunglobulin, a variety of biological responses are triggered including phagocytosis, antibody-dependent cellular cytotoxicity, endocytosis of soluble immune complexes, enhancement of antigen presentation, release of different cytokines. FcγRs are members of the immunoglobulin superfamily and three main classes, FcγRI, FcγRII and FcγRIII are recognised in man in different isoforms. The various genetic polymorphism of the receptors provide the receptor heterogeneity in the different cellular functions and may influence the pathogenesis and process of different diseases involving the change of the immune system.

Original languageHungarian
Pages (from-to)688-694
Number of pages7
JournalLege Artis Medicinae
Volume8
Issue number10
Publication statusPublished - 1998

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Fc Receptors
Immune System
Immunoglobulin G
Antigen Presentation
Genetic Polymorphisms
Endocytosis
Antigen-Antibody Complex
Phagocytosis
Immunoglobulins
Protein Isoforms
Cytokines
Antibodies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A human Fcγ-receptorok jellemzoi, szerepuk es klinikai jelentoseguk. / Szűcs, G.; Kavai, M.; Szegedi, G.

In: Lege Artis Medicinae, Vol. 8, No. 10, 1998, p. 688-694.

Research output: Contribution to journalArticle

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