Characterisation of mixed lithium dodecyl sulphate/lithium perfluorooctanesulphonate pseudo-stationary phases in MEKC

András Varga, Mónika Huszár, Zsófia Dobos, E. Kiss, Anikó Horváth, M. Idei

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Lipophilicity and methylene selectivity of mixed pseudo-stationary phases (PSPs) (containing lithium dodecyl sulphate (LDS) and lithium perfluorooctanesulphonate (LiPFOS) in different molar ratios) applied in MEKC have been investigated. Micellar proportion (tprop;mic, a quantity expressing that how much time is spent by the analyte in the micellar phase related to its whole migration time), CLOGP50 value (showing the value of hydrophobicity of a molecule spending exactly 50% of its migration time in the PSP) and methylene selectivity have been determined for different LDS/LiPFOS mixed phases. Values of the above-mentioned parameters have been determined for analytes with different chemical structures (alkylbenzene and alkylphenone homologous series, alcohols). Good linear correlation was obtained between either the micellar proportion, CLOGP50, or methylene selectivity and the phase composition for the mixed phases. Lipophilicity and methylene selectivity of the mixed LDS/LiPFOS PSPs can be calculated and can continuously be changed by mixing the two single phases (LDS and LiPFOS) in the appropriate (and calculable) portion.

Original languageEnglish
Pages (from-to)1923-1928
Number of pages6
JournalElectrophoresis
Volume30
Issue number11
DOIs
Publication statusPublished - Jun 2009

Fingerprint

Micellar Electrokinetic Capillary Chromatography
Lithium
Hydrophobicity
Hydrophobic and Hydrophilic Interactions
Phase composition
Alcohols
Molecules
dodecyl sulfate
perfluorooctane sulfonic acid

Keywords

  • MEKC
  • Methylene selectivity
  • Micellar phase residence time
  • Micellar proportion
  • Mixed pseudo-stationary phase

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry

Cite this

Characterisation of mixed lithium dodecyl sulphate/lithium perfluorooctanesulphonate pseudo-stationary phases in MEKC. / Varga, András; Huszár, Mónika; Dobos, Zsófia; Kiss, E.; Horváth, Anikó; Idei, M.

In: Electrophoresis, Vol. 30, No. 11, 06.2009, p. 1923-1928.

Research output: Contribution to journalArticle

Varga, András ; Huszár, Mónika ; Dobos, Zsófia ; Kiss, E. ; Horváth, Anikó ; Idei, M. / Characterisation of mixed lithium dodecyl sulphate/lithium perfluorooctanesulphonate pseudo-stationary phases in MEKC. In: Electrophoresis. 2009 ; Vol. 30, No. 11. pp. 1923-1928.
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