Characterisation of Hungarian porcine circovirus 2 genomes associated with PMWS and PDNS cases

A. Dán, T. Molnár, I. Biksi, R. Glávits, M. Shaheim, B. Harrach

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The authors report the data of the first survey on the incidence of postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) in Hungary. A PCR method specific for the detection of porcine circovirus 2 (PCV-2) was developed, which proved to be suitable for diagnostic purposes. PCR screening of organ samples from pigs suspected to be affected with PMWS or PDNS revealed the presence of PCV-2 in 80% of the cases. Six PCV-2 genomes from Hungarian isolates were completely sequenced. Phylogenetic comparison with all the available PCV-2 sequences showed that porcine circoviruses circulating in Hungary are more variable than in several other European countries. Two Hungarian strains clustered together with the Spanish strains forming a distinct group; two others fell in a common group with the French, UK, and Dutch strains, whereas another two strains showed the closest relationship to two of the three known German PCV-2 sequences.

Original languageEnglish
Pages (from-to)551-562
Number of pages12
JournalActa Veterinaria Hungarica
Volume51
Issue number4
DOIs
Publication statusPublished - 2003

Fingerprint

Porcine Postweaning Multisystemic Wasting Syndrome
Circovirus
postweaning multisystemic wasting syndrome
Porcine circovirus-2
Dermatitis
dermatitis
kidney diseases
Genome
swine
genome
Hungary
Porcine circovirus
Polymerase Chain Reaction
screening
Swine
incidence
phylogeny

Keywords

  • Field strains
  • Hungary
  • PDNS
  • PMWS
  • Porcine circovirus
  • Virus phylogenetics

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Characterisation of Hungarian porcine circovirus 2 genomes associated with PMWS and PDNS cases. / Dán, A.; Molnár, T.; Biksi, I.; Glávits, R.; Shaheim, M.; Harrach, B.

In: Acta Veterinaria Hungarica, Vol. 51, No. 4, 2003, p. 551-562.

Research output: Contribution to journalArticle

Dán, A. ; Molnár, T. ; Biksi, I. ; Glávits, R. ; Shaheim, M. ; Harrach, B. / Characterisation of Hungarian porcine circovirus 2 genomes associated with PMWS and PDNS cases. In: Acta Veterinaria Hungarica. 2003 ; Vol. 51, No. 4. pp. 551-562.
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