Significant part of the genetic information contained in DNA sequences is coding different types of RNA molecules. In the process called transcription an RNA copy is made from a portion of one of the two DNA strands. Genom forming RNA synthesis called RNA replication will be discussed in the next chapter. This chapter is restricted to transcription. General features of transcription resemble those of replication. These similarities include the overall reaction, synthetic phases, conditions and direction of the synthesis and postsynthetic modifications. Among the differences the lower specificity of RNA polymerases (primer is not needed, repair does not take place), the conservative type of mechanism and the frequency of transcription are mentioned. In discussing transcription the usual practice is followed, namely prokaryotic transcription is discussed first then that of eukaryotes. Structural features of RNA are also reviewed.
|Translated title of the contribution||Chapters from the 'Transfer of biological information'. Chapter X. Transcription|
|Number of pages||9|
|Publication status||Published - Jan 1 1996|
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