Changes of some lipid and lipid peroxidation characteristics in obese people as a result of a low energy diet

E. Dworschák, A. Lugasi, G. Pados, G. Bíró, A. Zsinka

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In blood samples of 54 obese persons (13 men, 41 women) some lipid components, malondialdehyde (MDA), and the activities of free radical protecting enzymes superoxide-dismutase (SOD) and glutathione-peroxidase (GSHpx), were determined before and after a seven-day slimming diet of 2.1 MJ/day. Body weight, triglycerides, HDL-cholesterol, and HDL-3-cholesterol all decreased, total cholesterol increased after the seven days hospitalization. After continuing the slimming diet (5.0-6.3 MJ/day) at home, HDL-2-cholesterol increased and total cholesterol returned to the initial value after three months. MDA decreased in the groups of hyperlipoproteinemia II/a and II/b and also in the group with high cholesterol and triglyceride levels (above 5.7 and 2.7 mmol/l). Correlation coefficients refer to the dominant role of high TG in the intensity of lipid peroxidation. The activity of SOD fell after the slimming, independent of lipid parameters. GSHpx activity remained unchanged except a drop in the male participants having high cholesterol levels. The behavior of the free radical protecting enzymes needs further examination.

Original languageEnglish
Pages (from-to)207-215
Number of pages9
JournalZeitschrift für Ernährungswissenschaft
Volume27
Issue number4
DOIs
Publication statusPublished - Dec 1988

Fingerprint

low calorie diet
Nutrition
HDL Cholesterol
Lipid Peroxidation
lipid peroxidation
Cholesterol
cholesterol
Diet
Hypercholesterolemia
Malondialdehyde
Lipids
Superoxide Dismutase
Free Radicals
Triglycerides
lipids
Hyperlipoproteinemias
Enzymes
Glutathione Peroxidase
malondialdehyde
superoxide dismutase

Keywords

  • glutathione-peroxidase
  • hyperlipoproteinemia
  • lipid peroxidation
  • obesity
  • superoxide-dismutase

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Food Science

Cite this

Changes of some lipid and lipid peroxidation characteristics in obese people as a result of a low energy diet. / Dworschák, E.; Lugasi, A.; Pados, G.; Bíró, G.; Zsinka, A.

In: Zeitschrift für Ernährungswissenschaft, Vol. 27, No. 4, 12.1988, p. 207-215.

Research output: Contribution to journalArticle

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