Changes in thermal denaturation properties of the long head of the biceps during lifetime

G. Bognár, I. Szabó, Cs Pintér, E. Ligeti, D. Lőrinczy

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Long head of the biceps (LHB) is an intraarticular tendon component of the shoulder joint. The function of this tendon is complex. First, it is an origin of flexion in upper limb, and second it plays role in joint stabilisation during shoulder movements. Histological type of tendon tissues is connective tissue. The mechanical behaviour of connective tissue is primarily determined by the composition and organisation of collagens. In tendons, type I collagen is the principal structural element of the extracellular matrix, which acts to transmit force between bones or bone and muscle. Owing to the special localisation of this tendon, the intra-articular mechanical forces affect it to a considerable extent. The LHB is known as a source of pain in pathologic states of the shoulder joint. The goal of this study was to establish the calorimetric standards of the LHB in different ages, and to observe the changes of thermal properties of collagen during lifetime. LHB samples were taken from 38 cadavers (between ages 0 and 90 years) without macroscopic sign of shoulder pathology. DSC analyses were performed with SETARAM Micro DSC-II. The thermal denaturation parameters varied between Tm (°C): 57, ΔH (J/g): 0.26 (age: 0 year) and Tm (°C): 62.92, ΔH (J/g): 1.28 (age: 90 years). The ageing of collagenous tendon tissue can be clearly followed in changes of thermal denaturation properties. The knowledge of the ageing of normal collagen provides a good basis to analyse further the LHB pathology.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalJournal of Thermal Analysis and Calorimetry
Volume102
Issue number1
DOIs
Publication statusPublished - Oct 2010

Fingerprint

tendons
Denaturation
biopolymer denaturation
Tendons
collagens
shoulders
life (durability)
Tissue
connective tissue
Collagen
pathology
Pathology
bones
Bone
Aging of materials
pain
Collagen Type I
muscles
limbs
Muscle

Keywords

  • Ageing
  • Collagen
  • Differential scanning calorimetry
  • Long head of the biceps

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Condensed Matter Physics

Cite this

Changes in thermal denaturation properties of the long head of the biceps during lifetime. / Bognár, G.; Szabó, I.; Pintér, Cs; Ligeti, E.; Lőrinczy, D.

In: Journal of Thermal Analysis and Calorimetry, Vol. 102, No. 1, 10.2010, p. 65-68.

Research output: Contribution to journalArticle

@article{b09c5fdc47234c7490eb7b74c0b3ebec,
title = "Changes in thermal denaturation properties of the long head of the biceps during lifetime",
abstract = "Long head of the biceps (LHB) is an intraarticular tendon component of the shoulder joint. The function of this tendon is complex. First, it is an origin of flexion in upper limb, and second it plays role in joint stabilisation during shoulder movements. Histological type of tendon tissues is connective tissue. The mechanical behaviour of connective tissue is primarily determined by the composition and organisation of collagens. In tendons, type I collagen is the principal structural element of the extracellular matrix, which acts to transmit force between bones or bone and muscle. Owing to the special localisation of this tendon, the intra-articular mechanical forces affect it to a considerable extent. The LHB is known as a source of pain in pathologic states of the shoulder joint. The goal of this study was to establish the calorimetric standards of the LHB in different ages, and to observe the changes of thermal properties of collagen during lifetime. LHB samples were taken from 38 cadavers (between ages 0 and 90 years) without macroscopic sign of shoulder pathology. DSC analyses were performed with SETARAM Micro DSC-II. The thermal denaturation parameters varied between Tm (°C): 57, ΔH (J/g): 0.26 (age: 0 year) and Tm (°C): 62.92, ΔH (J/g): 1.28 (age: 90 years). The ageing of collagenous tendon tissue can be clearly followed in changes of thermal denaturation properties. The knowledge of the ageing of normal collagen provides a good basis to analyse further the LHB pathology.",
keywords = "Ageing, Collagen, Differential scanning calorimetry, Long head of the biceps",
author = "G. Bogn{\'a}r and I. Szab{\'o} and Cs Pint{\'e}r and E. Ligeti and D. Lőrinczy",
year = "2010",
month = "10",
doi = "10.1007/s10973-009-0538-x",
language = "English",
volume = "102",
pages = "65--68",
journal = "Journal of Thermal Analysis and Calorimetry",
issn = "1388-6150",
publisher = "Springer Netherlands",
number = "1",

}

TY - JOUR

T1 - Changes in thermal denaturation properties of the long head of the biceps during lifetime

AU - Bognár, G.

AU - Szabó, I.

AU - Pintér, Cs

AU - Ligeti, E.

AU - Lőrinczy, D.

PY - 2010/10

Y1 - 2010/10

N2 - Long head of the biceps (LHB) is an intraarticular tendon component of the shoulder joint. The function of this tendon is complex. First, it is an origin of flexion in upper limb, and second it plays role in joint stabilisation during shoulder movements. Histological type of tendon tissues is connective tissue. The mechanical behaviour of connective tissue is primarily determined by the composition and organisation of collagens. In tendons, type I collagen is the principal structural element of the extracellular matrix, which acts to transmit force between bones or bone and muscle. Owing to the special localisation of this tendon, the intra-articular mechanical forces affect it to a considerable extent. The LHB is known as a source of pain in pathologic states of the shoulder joint. The goal of this study was to establish the calorimetric standards of the LHB in different ages, and to observe the changes of thermal properties of collagen during lifetime. LHB samples were taken from 38 cadavers (between ages 0 and 90 years) without macroscopic sign of shoulder pathology. DSC analyses were performed with SETARAM Micro DSC-II. The thermal denaturation parameters varied between Tm (°C): 57, ΔH (J/g): 0.26 (age: 0 year) and Tm (°C): 62.92, ΔH (J/g): 1.28 (age: 90 years). The ageing of collagenous tendon tissue can be clearly followed in changes of thermal denaturation properties. The knowledge of the ageing of normal collagen provides a good basis to analyse further the LHB pathology.

AB - Long head of the biceps (LHB) is an intraarticular tendon component of the shoulder joint. The function of this tendon is complex. First, it is an origin of flexion in upper limb, and second it plays role in joint stabilisation during shoulder movements. Histological type of tendon tissues is connective tissue. The mechanical behaviour of connective tissue is primarily determined by the composition and organisation of collagens. In tendons, type I collagen is the principal structural element of the extracellular matrix, which acts to transmit force between bones or bone and muscle. Owing to the special localisation of this tendon, the intra-articular mechanical forces affect it to a considerable extent. The LHB is known as a source of pain in pathologic states of the shoulder joint. The goal of this study was to establish the calorimetric standards of the LHB in different ages, and to observe the changes of thermal properties of collagen during lifetime. LHB samples were taken from 38 cadavers (between ages 0 and 90 years) without macroscopic sign of shoulder pathology. DSC analyses were performed with SETARAM Micro DSC-II. The thermal denaturation parameters varied between Tm (°C): 57, ΔH (J/g): 0.26 (age: 0 year) and Tm (°C): 62.92, ΔH (J/g): 1.28 (age: 90 years). The ageing of collagenous tendon tissue can be clearly followed in changes of thermal denaturation properties. The knowledge of the ageing of normal collagen provides a good basis to analyse further the LHB pathology.

KW - Ageing

KW - Collagen

KW - Differential scanning calorimetry

KW - Long head of the biceps

UR - http://www.scopus.com/inward/record.url?scp=78649746851&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649746851&partnerID=8YFLogxK

U2 - 10.1007/s10973-009-0538-x

DO - 10.1007/s10973-009-0538-x

M3 - Article

AN - SCOPUS:78649746851

VL - 102

SP - 65

EP - 68

JO - Journal of Thermal Analysis and Calorimetry

JF - Journal of Thermal Analysis and Calorimetry

SN - 1388-6150

IS - 1

ER -