Changes in the serotypes of Hungarian pneumococci isolated mainly from invasive infections: A review of all available data between 1988 and 2011

Adrienn Tóthpál, Krisztina Laub, Szilvia Kardos, K. Nagy, Orsolya Dobay

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Streptococcus pneumoniae is responsible for a high level of morbidity and mortality, especially among children. For a long time, only the polysaccharide vaccine was available against pneumococcal infections, but in the last decade special conjugate vaccines were developed for paediatric use. These vaccines have made a deep impact on serotype distribution all over the world, by suppressing those serotypes included in the vaccines, while new, previously rare types emerged. These changes have been monitored closely in numerous publications all over the world. Nevertheless, data on pneumococcal serotypes in Hungary were mostly published in Hungarian, therefore not available in the international literature. In this meta-analysis, our aim was to collect and summarise all available data, and try to follow the changes observed after the introduction of the conjugate vaccines.

Original languageEnglish
Pages (from-to)423-433
Number of pages11
JournalActa Microbiologica et Immunologica Hungarica
Volume59
Issue number3
DOIs
Publication statusPublished - Sep 1 2012

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Streptococcus pneumoniae
Conjugate Vaccines
Vaccines
Infection
Pneumococcal Infections
Hungary
Polysaccharides
Publications
Meta-Analysis
Pediatrics
Morbidity
Mortality
Serogroup

Keywords

  • pneumococcus
  • serotypes
  • vaccine coverage

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Medicine(all)

Cite this

Changes in the serotypes of Hungarian pneumococci isolated mainly from invasive infections : A review of all available data between 1988 and 2011. / Tóthpál, Adrienn; Laub, Krisztina; Kardos, Szilvia; Nagy, K.; Dobay, Orsolya.

In: Acta Microbiologica et Immunologica Hungarica, Vol. 59, No. 3, 01.09.2012, p. 423-433.

Research output: Contribution to journalArticle

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