Changes in the nutritional state and immune-serological parameters of esophagectomized patients fed jejunely with glutamine-poor and glutamine-rich nutriments

J. Hallay, G. Kovács, S. Kiss Sz, M. Farkas, G. Lakos, S. Sipka, E. Bodolay, P. Sápy

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background/Aims: In our former study we investigated the effect of glutamine-rich (I) and glutamine-poor (II) jejunal diet in operated patients with acute pancreatitis. In the glutamine-rich diet group clinical benefit and fast recovery og IgG, IgM, serum proteins, retinol-binding protein, albumin could be measured. In the present study the effects of the two types of jejunal diets I and II have been compared on the basis of changes in some immune parameters of 36 patients treated with subtotal esophagectomy for malignancy. Methodology: In randomized controlled trial data of two groups, I. patients with glutamine-rich Stresson Multi Fibre diet (23 patients) and II. patients with Nutrison Multi Fibre glutamine-poor diet (13 patients) were analyzed. Levels of serum proteins were measured by laser nephelometry, CD markers of lymphocytes by flow cytometry, phagocyte activity by chemiluminescence. Results: Level of proteins decreased on the 2nd postoperative day in both groups, then gradually increased postoperatively. In increase of level of serum protein, retinol-binding protein, prealbumin there was no difference between the two groups. Conclusions: In patients treated with subtotal esophagectomy, the glutamine-rich enteric diet did not result in faster recovery in levels of prealbumin, retinol-binding protein, immunglobulins and in outcome of patients than the glutamine-poor nutriment.

Original languageEnglish
Pages (from-to)1555-1559
Number of pages5
JournalHepato-Gastroenterology
Volume49
Issue number48
Publication statusPublished - Nov 1 2002

Keywords

  • Esophagectomy
  • Immunoglobulin
  • Nutrison multi fibre
  • Serum protein
  • Stresson multi fibre

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Fingerprint Dive into the research topics of 'Changes in the nutritional state and immune-serological parameters of esophagectomized patients fed jejunely with glutamine-poor and glutamine-rich nutriments'. Together they form a unique fingerprint.

  • Cite this