Changes in blood glucose level induced by sodium dodecylbenzene sulfonate (SDBS) in rats

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Abstract

Male and female rats were fed SDBS (0,25 g/kg body weight/day) for three months. At the end of the 3rd month both the control and experimental group was orally loaded with detergent, or glucose, or detergent and glucose. Due to the effect of a single large dose of detergent loading both in the experimental and the control group the curves of blood glucose levels followed similar time course to the one observed after glucose loading. After a glucose loading the blood glucose levels were higher in the 30th minute in the detergent pretreated female rats, whereas in the 90th minute they were lower as related to those of the controls. The blood glucose levels were higher at the beginning and lower at the end of the experimential period in the detergent and glucose treated male group as compared to the levels of the glucose loaded males. In female groups after glucose and detergent loading even in the controls, but particularly in the detergent pretreated group the levels of blood glucose exceeded the value of 150 mg per cent in several instances.

Original languageEnglish
Pages (from-to)144-151
Number of pages8
JournalZeitschrift für Ernährungswissenschaft
Volume12
Issue number2
DOIs
Publication statusPublished - Jun 1 1973

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Biochemistry

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