A dopamin transzporter (DAT) aktivitás változása bupropion hatasara 99mTc-TRODAT-1 spect vizsgálat depresszióban.

Translated title of the contribution: Change of dopamine transporter activity (DAT) during the action of bupropion (in depression)

Zoltán Szabó, Miklós Argyelán, Balázs Kanyó, László Pávics, Zoltán Janka

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Bupropion has an antidepressant effect through blocking the dopamine transporter. By 99mTc-TRODAT-SPECT, we measured the baseline DAT activity of depressed patients. After 3 weeks' bupropion treatment we studied the change in DAT activity, which corresponds to the occupancy of bupropion. The average occupancy of bupropion on DAT was similar to the international findings at 20.84% in 9 depressed patients.

Translated title of the contributionChange of dopamine transporter activity (DAT) during the action of bupropion (in depression)
Original languageHungarian
Pages (from-to)79-81
Number of pages3
JournalNeuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja = official journal of the Hungarian Association of Psychopharmacology
Volume6
Issue number2
Publication statusPublished - Jun 2004

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Change of dopamine transporter activity (DAT) during the action of bupropion (in depression)'. Together they form a unique fingerprint.

  • Cite this