Change in the distribution of acetylcholinesterase molecular forms in the rat superior cervical ganglion after NaBr treatment in vivo

Z. Rakonczay, P. Kása, J. R. Wolff

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Acetylcholinesterase (AChE) activity and the distribution of its molecular forms were investigated in the superior cervical ganglion of adult rats that had been given 27 mM bromide in drinking water for periods ranging from 2 days to 2 months. Chronic bromide treatment of adult rat caused an approx. 20% inhibition of the AChE activity in the superior cervical ganglion, while there was a significant elevation in the relative amount of the A12AChE molecular form (146%, P < 0.01). The results suggest that the bromide-induced formation of non-innervated postsynaptic membrane thickenings may promote the accumulation of A12AChE.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalNeurochemistry international
Volume15
Issue number2
DOIs
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Cell Biology

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