Change in insulin binding capacity of plasma membrane and nuclear envelope of Tetrahymena following a single long-term pretreatment and several short-term pretreatments (imprinting) with insulin.

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Abstract

Following insulin pretreatment (hormonal imprinting) of Tetrahymena cells there was an increased binding of insulin both in the plasma membrane and in the nuclear envelope of the offspring generations. A short (1 x 15 min) treatment did not produce imprinting in the plasma membrane but a 1 h treatment was sufficient. A similar short (1 x 15 min) treatment was enough to develop imprinting in the nuclear envelope and this is the treatment which induced the highest response. In the nuclear membrane there was a significant difference in the effect of 4 x 15 min and 1 x 60 min treatments but there was no effect in the plasma membrane. The effect of imprinting was observed after 48 h (16-20 generations). The repeated treatment of imprinted cells did not induce a further increase in the binding of the hormone.

Original languageEnglish
Pages (from-to)189-194
Number of pages6
JournalCytobios
Volume79
Issue number318
Publication statusPublished - 1994

Fingerprint

Tetrahymena
imprinting
Nuclear Envelope
nuclear membrane
binding capacity
insulin
plasma membrane
pretreatment
Cell Membrane
Insulin
membrane
plasma
hormones
Hormones
cells
hormone
effect

ASJC Scopus subject areas

  • Aquatic Science
  • Cell Biology

Cite this

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title = "Change in insulin binding capacity of plasma membrane and nuclear envelope of Tetrahymena following a single long-term pretreatment and several short-term pretreatments (imprinting) with insulin.",
abstract = "Following insulin pretreatment (hormonal imprinting) of Tetrahymena cells there was an increased binding of insulin both in the plasma membrane and in the nuclear envelope of the offspring generations. A short (1 x 15 min) treatment did not produce imprinting in the plasma membrane but a 1 h treatment was sufficient. A similar short (1 x 15 min) treatment was enough to develop imprinting in the nuclear envelope and this is the treatment which induced the highest response. In the nuclear membrane there was a significant difference in the effect of 4 x 15 min and 1 x 60 min treatments but there was no effect in the plasma membrane. The effect of imprinting was observed after 48 h (16-20 generations). The repeated treatment of imprinted cells did not induce a further increase in the binding of the hormone.",
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journal = "Cytobios",
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T1 - Change in insulin binding capacity of plasma membrane and nuclear envelope of Tetrahymena following a single long-term pretreatment and several short-term pretreatments (imprinting) with insulin.

AU - Hegyesi, H.

AU - Csaba, G.

PY - 1994

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N2 - Following insulin pretreatment (hormonal imprinting) of Tetrahymena cells there was an increased binding of insulin both in the plasma membrane and in the nuclear envelope of the offspring generations. A short (1 x 15 min) treatment did not produce imprinting in the plasma membrane but a 1 h treatment was sufficient. A similar short (1 x 15 min) treatment was enough to develop imprinting in the nuclear envelope and this is the treatment which induced the highest response. In the nuclear membrane there was a significant difference in the effect of 4 x 15 min and 1 x 60 min treatments but there was no effect in the plasma membrane. The effect of imprinting was observed after 48 h (16-20 generations). The repeated treatment of imprinted cells did not induce a further increase in the binding of the hormone.

AB - Following insulin pretreatment (hormonal imprinting) of Tetrahymena cells there was an increased binding of insulin both in the plasma membrane and in the nuclear envelope of the offspring generations. A short (1 x 15 min) treatment did not produce imprinting in the plasma membrane but a 1 h treatment was sufficient. A similar short (1 x 15 min) treatment was enough to develop imprinting in the nuclear envelope and this is the treatment which induced the highest response. In the nuclear membrane there was a significant difference in the effect of 4 x 15 min and 1 x 60 min treatments but there was no effect in the plasma membrane. The effect of imprinting was observed after 48 h (16-20 generations). The repeated treatment of imprinted cells did not induce a further increase in the binding of the hormone.

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