Centromera-szétválás és malignitás.

Translated title of the contribution: Centromere separation and malignancy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The centromeres of human chromosomes separate according to a "normal sequence" during mitosis. "Out-of-phase" separation and especially premature centromere division may lead to aneuploidy, and may be regarded as a manifestation of chromosome instability. Evaluation of these phenomena may contribute to a better understanding of predisposition to malignancy and to the possible screening of family members at high risk of cancer. For this reason, a more up-to-date and meticulous research of regulation and clinical significance of centromere separation is warranted.

Original languageHungarian
Pages (from-to)2479-2481
Number of pages3
JournalOrvosi Hetilap
Volume141
Issue number46
Publication statusPublished - Nov 12 2000

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Centromere
Neoplasms
Chromosomal Instability
Human Chromosomes
Aneuploidy
Mitosis
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Centromera-szétválás és malignitás. / Méhes, K.

In: Orvosi Hetilap, Vol. 141, No. 46, 12.11.2000, p. 2479-2481.

Research output: Contribution to journalArticle

Méhes, K 2000, 'Centromera-szétválás és malignitás.', Orvosi Hetilap, vol. 141, no. 46, pp. 2479-2481.
Méhes, K. / Centromera-szétválás és malignitás. In: Orvosi Hetilap. 2000 ; Vol. 141, No. 46. pp. 2479-2481.
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