CELL‐MEDIATED IMMUNITY TO HERPES VIRUS TYPE‐1 IN PATIENTS WITH RECURRENT CORNEAL HERPES SIMPLEX

HELGA HAMMER, ATTILA DOBOZY

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Abstract

The proportion of T lymphocytes in the peripheral blood, their phytohae‐magglutinin reactivity, and the leycocyte migration inhibitory effect of purified tuberculin protein were found to be equal in 25 recurrent corneal herpes simplex patients and 17 healthy individuals who had never suffered from clinically manifest herpes simplex virus (HSV) infection. Conversely, the HSV vaccine inhibited the leucocyte migration in the healthy group, but not in the recurrent herpes patients when the clinical symptoms were manifest. In 14 recurrent corneal herpes simplex patients, the examinations were repeated after a 3‐month symptom‐free period, and in these periods the patients corresponded equally to the healthy group in every respect. 1980 Institution Acta Ophthalmologica Scandinavica

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalActa Ophthalmologica
Volume58
Issue number2
DOIs
Publication statusPublished - Apr 1980

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Keywords

  • cell‐mediated immunity
  • corneal herpes
  • herpes simplex virus

ASJC Scopus subject areas

  • Ophthalmology

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