Cathepsin d activity in otosclerotic bone and perilymph

Ottó Ribári, I. Sziklai

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Otosclerotic bone and perilymph samples obtained during stapedectomy operations from patients suffering from pure conductive hearing loss of at least 40 dBs air-bone gap at 500 Hz. Control perilymph samples derived from patients suffering from round window membrane rupture or Meniere's disease. Enzyme activities were determined using a synthetic fluorogenic substrate by fluorescence spectrophotometry. No significant differences have been found between the protein content of otosclerotic and normal or non-otosclerotic perilymph samples. Cathepsin D activity was significantly higher (p

Original languageEnglish
Pages (from-to)549-552
Number of pages4
JournalActa Oto-Laryngologica
Volume105
Issue number5-6
DOIs
Publication statusPublished - 1988

Fingerprint

Perilymph
Cathepsins
Bone and Bones
Stapes Surgery
Conductive Hearing Loss
Cathepsin D
Meniere Disease
Fluorescence Spectrometry
Fluorescent Dyes
Rupture
Air
Membranes
Enzymes
Proteins

Keywords

  • Cathepsin D
  • Glucosaminoglycans
  • Otosclerosis
  • Perilymph

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Cathepsin d activity in otosclerotic bone and perilymph. / Ribári, Ottó; Sziklai, I.

In: Acta Oto-Laryngologica, Vol. 105, No. 5-6, 1988, p. 549-552.

Research output: Contribution to journalArticle

Ribári, Ottó ; Sziklai, I. / Cathepsin d activity in otosclerotic bone and perilymph. In: Acta Oto-Laryngologica. 1988 ; Vol. 105, No. 5-6. pp. 549-552.
@article{2d164cdf5a4f4e709636ad2ef7bc5e92,
title = "Cathepsin d activity in otosclerotic bone and perilymph",
abstract = "Otosclerotic bone and perilymph samples obtained during stapedectomy operations from patients suffering from pure conductive hearing loss of at least 40 dBs air-bone gap at 500 Hz. Control perilymph samples derived from patients suffering from round window membrane rupture or Meniere's disease. Enzyme activities were determined using a synthetic fluorogenic substrate by fluorescence spectrophotometry. No significant differences have been found between the protein content of otosclerotic and normal or non-otosclerotic perilymph samples. Cathepsin D activity was significantly higher (p",
keywords = "Cathepsin D, Glucosaminoglycans, Otosclerosis, Perilymph",
author = "Ott{\'o} Rib{\'a}ri and I. Sziklai",
year = "1988",
doi = "10.3109/00016488809119518",
language = "English",
volume = "105",
pages = "549--552",
journal = "Acta Oto-Laryngologica",
issn = "0001-6489",
publisher = "Informa Healthcare",
number = "5-6",

}

TY - JOUR

T1 - Cathepsin d activity in otosclerotic bone and perilymph

AU - Ribári, Ottó

AU - Sziklai, I.

PY - 1988

Y1 - 1988

N2 - Otosclerotic bone and perilymph samples obtained during stapedectomy operations from patients suffering from pure conductive hearing loss of at least 40 dBs air-bone gap at 500 Hz. Control perilymph samples derived from patients suffering from round window membrane rupture or Meniere's disease. Enzyme activities were determined using a synthetic fluorogenic substrate by fluorescence spectrophotometry. No significant differences have been found between the protein content of otosclerotic and normal or non-otosclerotic perilymph samples. Cathepsin D activity was significantly higher (p

AB - Otosclerotic bone and perilymph samples obtained during stapedectomy operations from patients suffering from pure conductive hearing loss of at least 40 dBs air-bone gap at 500 Hz. Control perilymph samples derived from patients suffering from round window membrane rupture or Meniere's disease. Enzyme activities were determined using a synthetic fluorogenic substrate by fluorescence spectrophotometry. No significant differences have been found between the protein content of otosclerotic and normal or non-otosclerotic perilymph samples. Cathepsin D activity was significantly higher (p

KW - Cathepsin D

KW - Glucosaminoglycans

KW - Otosclerosis

KW - Perilymph

UR - http://www.scopus.com/inward/record.url?scp=0023898233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023898233&partnerID=8YFLogxK

U2 - 10.3109/00016488809119518

DO - 10.3109/00016488809119518

M3 - Article

C2 - 3400459

AN - SCOPUS:0023898233

VL - 105

SP - 549

EP - 552

JO - Acta Oto-Laryngologica

JF - Acta Oto-Laryngologica

SN - 0001-6489

IS - 5-6

ER -