Caspofungin susceptibility testing of Candida inconspicua: Correlation of different methods with the minimal fungicidal concentration

L. Majoros, G. Kardos, B. Szabó, M. Sipiczki

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Minimal inhibitory and minimal fungicidal concentrations of caspofungin were determined for 48 Candida inconspicua isolates. By using CLSI (formerly NCCLS) methodology with the partial inhibition endpoint criterion, caspofungin exhibited a good fungicidal effect against C. inconspicua (the MIC90 was 0.25 μg/ml and the minimum fungicidal concentration [MFC] was 0.5 μg/ml after 24 h). Total inhibition yielded falsely elevated MICs, exceeding even the respective MFCs.

Original languageEnglish
Pages (from-to)3486-3488
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume49
Issue number8
DOIs
Publication statusPublished - Aug 1 2005

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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