Cardiac hypertrophy and diastolic function in physically well trained and in obese men

Z. Sidó, P. Jákó, Zs Kneffel, Zs Kispéter, G. Pavlik

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

OBJECTIVE: The aim of the present study was to compare cardiac hypertrophy and diastolic function in extremely obese male patients and physically active adult male subjects of similar age (means 43.0-43.4 y). DESIGN: Data of male patients referred to our hospital ward in order to reduce their body weight (BW) were compared with those of physically active and nonactive healthy males. SUBJECTS: The groups contained 21-24 male subjects, very active and moderately active subjects taking part in regular competitive or leisure time physical activity were in the two athletic groups, severely overweight patients constituted the obese group and healthy persons served as controls. MEASUREMENTS: Two-dimensionally guided M-mode and Doppler recordings. RESULTS: In comparison with the controls, obese patients had larger left atrial systolic and left ventricular (LV) diastolic internal diameters, LV diastolic wall thickness and muscle mass. Of the body size-related indices, only the left atrial systolic diameter index was significantly higher. LV systolic and diastolic functions were impaired as indicated by a decreased ejection fraction (EF), higher heart rate (HR), decreased E/A quotient and increased isovolumetric relaxation time. In the physically very active subjects, a thicker LV diastolic wall was seen without LV dilatation. Body size-related wall thickness and muscle mass were significantly higher than in the controls. EF and HR did not differ from those of the controls. CONCLUSION: The most useful help to distinguish between physiological and pathological left ventricular hypertrophy can be to investigate diastolic functions. The most salient difference appeared in diastolic function, because E/A quotient was higher in the very active subjects than in the controls and it was the lowest in the obese persons.

Original languageEnglish
Pages (from-to)1347-1352
Number of pages6
JournalInternational Journal of Obesity
Volume27
Issue number11
DOIs
Publication statusPublished - Nov 2003

Fingerprint

Cardiomegaly
hypertrophy
Body Size
heart rate
body size
Heart Rate
Muscles
muscles
Leisure Activities
Left Ventricular Hypertrophy
sports
physical activity
Sports
Dilatation
Relaxation
Body Weight
Exercise
body weight

Keywords

  • Athlete's heart
  • Echocardiography
  • Middle-aged males

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Food Science
  • Endocrinology, Diabetes and Metabolism

Cite this

Cardiac hypertrophy and diastolic function in physically well trained and in obese men. / Sidó, Z.; Jákó, P.; Kneffel, Zs; Kispéter, Zs; Pavlik, G.

In: International Journal of Obesity, Vol. 27, No. 11, 11.2003, p. 1347-1352.

Research output: Contribution to journalArticle

Sidó, Z. ; Jákó, P. ; Kneffel, Zs ; Kispéter, Zs ; Pavlik, G. / Cardiac hypertrophy and diastolic function in physically well trained and in obese men. In: International Journal of Obesity. 2003 ; Vol. 27, No. 11. pp. 1347-1352.
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