An in vivo mouse model was developed in order to study the characteristics of secondary tumor induction by cytostatic drug combinations used in human anticancer treatment. In this model we have proved the carcino-leukemogenic effects of widely used chemotherapeutical drug combinations (CHOP, COPP, COPBLAM, VAM). The carcinogenic hazards of cyclophosphamide and other alkylating drugs could also be demonstrated in our model.
|Number of pages||5|
|Publication status||Published - Jan 1 1995|
- Cytostatic combinations
- Secondary tumors
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)