Carcinogenic effects of cytostatic protocols in CBA/Ca mice

I. Ember, T. Raposa, C. Varga, L. Herceg, I. Kiss

Research output: Contribution to journalArticle

19 Citations (Scopus)


An in vivo mouse model was developed in order to study the characteristics of secondary tumor induction by cytostatic drug combinations used in human anticancer treatment. In this model we have proved the carcino-leukemogenic effects of widely used chemotherapeutical drug combinations (CHOP, COPP, COPBLAM, VAM). The carcinogenic hazards of cyclophosphamide and other alkylating drugs could also be demonstrated in our model.

Original languageEnglish
Pages (from-to)65-69
Number of pages5
JournalIn Vivo
Issue number1
Publication statusPublished - Jan 1 1995


  • Cyclophosphamide
  • Cytostatic combinations
  • Secondary tumors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology

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    Ember, I., Raposa, T., Varga, C., Herceg, L., & Kiss, I. (1995). Carcinogenic effects of cytostatic protocols in CBA/Ca mice. In Vivo, 9(1), 65-69.