Carbohydrate components of flavonol triaosides: A convenient synthesis of O-α-l-rhamnopyranosyl-(1→3)-O-α-l-rhamnopyranosyl-(1→6)-d-Galactose and O-α-l-rhamnopyranosyl-(1→2)-O-α-l-rhamnopyranosyl-(1→6)-d-galactose

András Lipták, Pál Nánási, András Neszmélyi, Ingrid Riess-Maurer, Hildebert Wagner

Research output: Contribution to journalArticle

11 Citations (Scopus)


Condensation of 1,2:3,4-di-O-isopropylidene-α-d-galactopyranose (1) with 2,4-di-O-acetyl-3-O-(2,3,4-tri-O-acetyl-α-l-rhamnopyranosyl)-α-l-rhamnopyranosyl bromide (2), followed by subsequent removal of the isopropylidene and acetyl groups from the product, afforded the first of the title trisaccharides. The reaction of 1 with 3,4-di-O-benzyl-2-O-p-nitrobenzoyl-α-l-rhamnopyranosyl bromide and deacylation of the product gave a disaccharide derivative that was treated with 2,3,4-tri-O-acetyl-α-l-rhamnopyranosyl bromide. Removal of the protecting groups from the product gave the second (15) of the title trisaccharides. The reaction of 1 with the acetobromo derivative of 2-O-α-l-rhamnopyranosyl-l-rhamnose, with subsequent removal of protecting groups from the product, also gave trisaccharide 15.

Original languageEnglish
Pages (from-to)43-52
Number of pages10
JournalCarbohydrate Research
Issue number1
Publication statusPublished - Jun 16 1981


ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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