Capillary density of tenotomized skeletal muscles - I. Experimental study in the rat

L. Józsa, M. JÄrvinen, M. Kvist, M. Lehto, A. Mikola

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Our purpose was to study the capillary density of rat gastrocnemius muscle by microangiography 7-21 days after achillotenotomy or immobilization in a plaster cast. Sixten animals were tenotomized, 12 immobilized in a plaster cast, and 4 served as controls. The number of capillaries was counted per 1,000 muscle fibers from each sample. No site differences were found in control muscles, where on an average 1,250 capillaries per 1,000 muscle fibers were found. After tenotomy the number of capillaries was decreased 35%, 31%, and 32% on days 7, 14, and 21, respectively. In immobilized muscles the decrease in capillary density occurred slowly, the corresponding decrease being 23%, 33%, and 28% on days 7, 14, and 21, respectively. These results indicate that the capillary density of muscular tissue is greatly decreased following the disuse produced by tenotomy or immobilization.

Original languageEnglish
Pages (from-to)175-181
Number of pages7
JournalEuropean Journal of Applied Physiology and Occupational Physiology
Volume44
Issue number2
DOIs
Publication statusPublished - Aug 1 1980

Keywords

  • Capillary density
  • Immobilization
  • Skeletal muscles
  • Tenotomy

ASJC Scopus subject areas

  • Physiology
  • Public Health, Environmental and Occupational Health

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