Calorimetric examination of hip pseudo-capsule after secondary hip surgeries

G. Bűcs, L. G. Nőt, Dandé, L. Kereskai, D. Lőrinczy

Research output: Contribution to journalArticle

Abstract

During revision hip surgeries, a soft pseudo-capsule is formed around the artificial joint. The roles of the pseudo-capsule are to protect and to stabilize the joint. Based on intraoperative observation, we have found that different types of pseudo-capsules have different thickness and elasticity, compared to the primary joint capsule. The purpose of the study was to evaluate and identify the different types of pseudo-capsules, based on thermal characteristics and histological examinations. The pseudo-capsule samples were collected during aseptic hip revision (n = 3), septic hip revision (n = 2) and during revision surgery after antibiotic-impregnated spacer implantation (n = 3). The thermal characteristics (maximal denaturation temperature, T m , and calorimetric enthalpy change, ΔH cal ) were determined from the measurements made by SETARAM Micro DSC-II calorimeter between 37° and 90°C with 0.3 K min −1 heating rate. The denaturation scans of different pseudo-capsule samples have clearly demonstrated specific, representative changes, comparing samples with aseptic and septic origins. These changes were confirmed by histological evaluations; therefore, DSC could be a useful tool in the evaluation of hip pseudo-capsules with different origins, providing further help in the differential diagnostics of septic conditions.

Original languageEnglish
JournalJournal of Thermal Analysis and Calorimetry
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

capsules
surgery
Surgery
Capsules
examination
Denaturation
biopolymer denaturation
evaluation
antibiotics
Calorimeters
Heating rate
spacers
calorimeters
Enthalpy
Elasticity
implantation
elastic properties
enthalpy
Anti-Bacterial Agents
heating

Keywords

  • Calorimetry
  • Collagen
  • Hip replacement
  • Pseudo-capsule
  • Revision
  • Sepsis

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

Cite this

Calorimetric examination of hip pseudo-capsule after secondary hip surgeries. / Bűcs, G.; Nőt, L. G.; Dandé, ; Kereskai, L.; Lőrinczy, D.

In: Journal of Thermal Analysis and Calorimetry, 01.01.2019.

Research output: Contribution to journalArticle

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