Calcium-induced alkali cation transport in nucleated red cells

D. Marino, B. Sarkadi, G. Gardos, L. Bolis

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The effects of the calcium ionophore A23187 + Ca on the K and Na transport in the nucleated red cells of chicken and fish (Ctenopharyngodon idella) were investigated. A23187 + Ca induced a significant increase in the permeability of the cell membrane for both K+ and Na+, while A23187 + Mg was ineffective in this respect. Addition of EGTA or EDTA to the medium blocked the ionophore + Ca effect. Quinidine inhibited the A23187 + Ca-induced K and Na transport in the nucleated fish red cells, while ouabain was ineffective as an inhibitor. The relationship of the Ca-induced alkali cation transport in nucleated red cells to that in human red cells, and the possible role of this transport in volume regulation is discussed.

Original languageEnglish
Pages (from-to)295-300
Number of pages6
JournalMolecular Physiology
Volume1
Issue number5
Publication statusPublished - 1981

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Calcimycin
Alkalies
Cations
Cells
Calcium
Fish
Fishes
Cell Membrane Permeability
Quinidine
Calcium Ionophores
Egtazic Acid
Ionophores
Ouabain
Cell membranes
Edetic Acid
Chickens

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Calcium-induced alkali cation transport in nucleated red cells. / Marino, D.; Sarkadi, B.; Gardos, G.; Bolis, L.

In: Molecular Physiology, Vol. 1, No. 5, 1981, p. 295-300.

Research output: Contribution to journalArticle

Marino, D, Sarkadi, B, Gardos, G & Bolis, L 1981, 'Calcium-induced alkali cation transport in nucleated red cells', Molecular Physiology, vol. 1, no. 5, pp. 295-300.
Marino, D. ; Sarkadi, B. ; Gardos, G. ; Bolis, L. / Calcium-induced alkali cation transport in nucleated red cells. In: Molecular Physiology. 1981 ; Vol. 1, No. 5. pp. 295-300.
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