Calcipeniás osteopathia transzfúziós haemosiderosisban és idiopátiás haemochromatosisban.

Translated title of the contribution: Calcipenic osteopathy in transfusion hemosiderosis and idiopathic hemochromatosis

E. Czink, C. Horváth, A. A. Malek, G. Siklósi

Research output: Contribution to journalArticle

Abstract

Bone metabolism studies were performed on 5 patients with transfusion haemosiderosis (2 male, 3 female; mean age: 30.8 years) and 5 patients with idiopathic haemochromatosis (2 male, 3 female; mean age: 48.8 years). In the majority of the patients, the modern osteodensitometric method showed a significant decrease of the mineral content of the trabecular and cortical bones. Low calcitonin and dehydroepiandrosterone-sulphate concentrations were measured in the majority of the patients with calcipenic osteopathy. Besides marked bone loss, hypogonadotropic hypogonadism was found in 3 male patients, while normal LH, FSH concentration values were measured in 3 female patients. The prolactin concentration was normal in all 6 patients. The authors suppose that besides the already known pathogenetic factors, insufficient calcitonin effect and especially the partial lack of dehydroepiandrosterone-sulphate can play a role in the development of bone loss connected with iron overload. Further study with a greater number of patients in required to support the above findings.

Original languageHungarian
Pages (from-to)1187-1192
Number of pages6
JournalOrvosi Hetilap
Volume132
Issue number22
Publication statusPublished - Jun 2 1991

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Hemosiderosis
Hemochromatosis
Dehydroepiandrosterone Sulfate
Calcitonin
Bone and Bones
Iron Overload
Hypogonadism
Bone Development
Prolactin
Minerals

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Calcipeniás osteopathia transzfúziós haemosiderosisban és idiopátiás haemochromatosisban. / Czink, E.; Horváth, C.; Malek, A. A.; Siklósi, G.

In: Orvosi Hetilap, Vol. 132, No. 22, 02.06.1991, p. 1187-1192.

Research output: Contribution to journalArticle

Czink, E. ; Horváth, C. ; Malek, A. A. ; Siklósi, G. / Calcipeniás osteopathia transzfúziós haemosiderosisban és idiopátiás haemochromatosisban. In: Orvosi Hetilap. 1991 ; Vol. 132, No. 22. pp. 1187-1192.
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