Caffeine-resistance in Schizosaccharomyces pombe

a pleiotropic mutation affecting UV-sensitivity, fertility, and cell cycle

Z. Benkö, M. Sipiczki

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A stable mutant having increased resistance to growth inhibition by caffeine was obtained from Schizosaccharomyces pombe after UV-irradiation of vegetative cells. The caf1-21 mutation confers increased UV-sensitivity, impaired fertility and sporulation, lengthened cell cycle and a slightly abnormal cell morphology, but it does not affect ectopic recombination in vegetative cells. The mutation is partially dominant and defines a gene mapping on chromosome II. Various possible mechanisms of resistance are discussed.

Original languageEnglish
Pages (from-to)47-52
Number of pages6
JournalCurrent Genetics
Volume18
Issue number1
DOIs
Publication statusPublished - Jul 1990

Fingerprint

Schizosaccharomyces
Caffeine
Fertility
Cell Cycle
Mutation
Chromosome Mapping
Genetic Recombination
Chromosomes
Growth

Keywords

  • Caffeine-resistance
  • Cell cycle
  • Pleiotropic mutation
  • Schizosaccharomyces pombe

ASJC Scopus subject areas

  • Genetics

Cite this

Caffeine-resistance in Schizosaccharomyces pombe : a pleiotropic mutation affecting UV-sensitivity, fertility, and cell cycle. / Benkö, Z.; Sipiczki, M.

In: Current Genetics, Vol. 18, No. 1, 07.1990, p. 47-52.

Research output: Contribution to journalArticle

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