C9orf72 immunohistochemistry in Alzheimer's disease

Research output: Contribution to journalArticle

Abstract

Mutation in chromosome 9 open reading frame 72 (C9orf72) is a major genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), referred to as C9FTD/ALS. The function of the protein is currently unknown, and the pathomechanism of C9FTD/ALS remains to be elucidated. The study by Satoh and colleagues in the previous issue of Alzheimer's Research & Therapy presents important new findings on C9orf72 protein expression in neurodegenerative disorders along with characterization of C9orf72 antibodies.

Original languageEnglish
Article number37
JournalAlzheimer's Research and Therapy
Volume4
Issue number5
DOIs
Publication statusPublished - 2012

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Chromosomes, Human, Pair 9
Open Reading Frames
Alzheimer Disease
Immunohistochemistry
Amyotrophic Lateral Sclerosis
Neurodegenerative Diseases
Proteins
Mutation
Antibodies
Research
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Cognitive Neuroscience

Cite this

C9orf72 immunohistochemistry in Alzheimer's disease. / Hortobágyi, T.

In: Alzheimer's Research and Therapy, Vol. 4, No. 5, 37, 2012.

Research output: Contribution to journalArticle

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