Budapest Registry of Self-poisoned patients

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Abstract

The majority of persons attempting suicide are young (peak in the 17-19 age group), female (68%), otherwise healthy, and use chemicals for this purpose (self-poisoning); 98% of these persons survive. Thus, survivors of self-poisoning present a unique model for the study of somatic and germinal mutagenic effects of large doses of chemicals in human beings. This recognition prompted the establishment of the Budapest Registry of Self-poisoned Patients in 1990. The recorded 11 847 cases used 20 324 drugs in 1990-1992. Benzodiazepines were the most popular drugs for self-poisoning. International collaboration by the use of molecular epidemiological methods seems to be promising in the self-poisoning model.

Original languageEnglish
Pages (from-to)157-163
Number of pages7
JournalMutation Research/Environmental Mutagenesis and Related Subjects
Volume312
Issue number2
DOIs
Publication statusPublished - Apr 1994

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Keywords

  • Chemical mutagenesis
  • Germinal mutations
  • Self-poisoning model
  • Somatic mutations

ASJC Scopus subject areas

  • Toxicology
  • Genetics

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