Buchwald-Hartwig reactions of monohaloflavones

Krisztina Kónya, Dávid Pajtás, Attila Kiss-Szikszai, T. Patonay

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The article describes the amination of different monobromo- or monochloroflavones with primary and secondary alkylamines and aniline derivatives by Buchwald-Hartwig reaction. The influence of the phosphine ligands used is described. The use of amino acid derivatives as a nitrogen source is also demonstrated. This latter reaction allows the synthesis of unique flavone-amino-acid conjugates.

Original languageEnglish
Pages (from-to)828-839
Number of pages12
JournalEuropean Journal of Organic Chemistry
Volume2015
Issue number4
DOIs
Publication statusPublished - Jan 1 2015

Fingerprint

phosphine
flavone
amino acids
Derivatives
Amination
Amino Acids
aniline
phosphines
Nitrogen
Ligands
nitrogen
ligands
synthesis

Keywords

  • Amination
  • Amino acids
  • Cross-coupling
  • Homogeneous catalysis
  • Oxygen heterocycles
  • Palladium

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Buchwald-Hartwig reactions of monohaloflavones. / Kónya, Krisztina; Pajtás, Dávid; Kiss-Szikszai, Attila; Patonay, T.

In: European Journal of Organic Chemistry, Vol. 2015, No. 4, 01.01.2015, p. 828-839.

Research output: Contribution to journalArticle

Kónya, Krisztina ; Pajtás, Dávid ; Kiss-Szikszai, Attila ; Patonay, T. / Buchwald-Hartwig reactions of monohaloflavones. In: European Journal of Organic Chemistry. 2015 ; Vol. 2015, No. 4. pp. 828-839.
@article{e2e227ba17f74c61aa6406087cef4cb9,
title = "Buchwald-Hartwig reactions of monohaloflavones",
abstract = "The article describes the amination of different monobromo- or monochloroflavones with primary and secondary alkylamines and aniline derivatives by Buchwald-Hartwig reaction. The influence of the phosphine ligands used is described. The use of amino acid derivatives as a nitrogen source is also demonstrated. This latter reaction allows the synthesis of unique flavone-amino-acid conjugates.",
keywords = "Amination, Amino acids, Cross-coupling, Homogeneous catalysis, Oxygen heterocycles, Palladium",
author = "Krisztina K{\'o}nya and D{\'a}vid Pajt{\'a}s and Attila Kiss-Szikszai and T. Patonay",
year = "2015",
month = "1",
day = "1",
doi = "10.1002/ejoc.201403108",
language = "English",
volume = "2015",
pages = "828--839",
journal = "Annalen der Pharmacie",
issn = "0365-5490",
publisher = "Wiley-VCH Verlag",
number = "4",

}

TY - JOUR

T1 - Buchwald-Hartwig reactions of monohaloflavones

AU - Kónya, Krisztina

AU - Pajtás, Dávid

AU - Kiss-Szikszai, Attila

AU - Patonay, T.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The article describes the amination of different monobromo- or monochloroflavones with primary and secondary alkylamines and aniline derivatives by Buchwald-Hartwig reaction. The influence of the phosphine ligands used is described. The use of amino acid derivatives as a nitrogen source is also demonstrated. This latter reaction allows the synthesis of unique flavone-amino-acid conjugates.

AB - The article describes the amination of different monobromo- or monochloroflavones with primary and secondary alkylamines and aniline derivatives by Buchwald-Hartwig reaction. The influence of the phosphine ligands used is described. The use of amino acid derivatives as a nitrogen source is also demonstrated. This latter reaction allows the synthesis of unique flavone-amino-acid conjugates.

KW - Amination

KW - Amino acids

KW - Cross-coupling

KW - Homogeneous catalysis

KW - Oxygen heterocycles

KW - Palladium

UR - http://www.scopus.com/inward/record.url?scp=85027945690&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85027945690&partnerID=8YFLogxK

U2 - 10.1002/ejoc.201403108

DO - 10.1002/ejoc.201403108

M3 - Article

AN - SCOPUS:85027945690

VL - 2015

SP - 828

EP - 839

JO - Annalen der Pharmacie

JF - Annalen der Pharmacie

SN - 0365-5490

IS - 4

ER -