Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms

Yann Devos, Adinda de Schrijver, Patrick de Clercq, J. Kiss, Jörg Romeis

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

This review paper explores whether the cultivation of the genetically modified Bt-maize transformation event MON 88017, expressing the insecticidal Cry3Bb1 protein against corn rootworms (Coleoptera: Chrysomelidae), causes adverse effects to non-target organisms (NTOs) and the ecological and anthropocentric functions they provide. Available data do not reveal adverse effects of Cry3Bb1 on various NTOs that are representative of potentially exposed taxonomic and functional groups, confirming that the insecticidal activity of the Cry3Bb1 protein is limited to species belonging to the coleopteran family of Chrysomelidae. The potential risk to non-target chrysomelid larvae ingesting maize MON 88017 pollen deposited on host plants is minimal, as their abundance in maize fields and the likelihood of encountering harmful amounts of pollen in and around maize MON 88017 fields are low. Non-target adult chrysomelids, which may occasionally feed on maize MON 88017 plants, are not expected to be affected due to the low activity of the Cry3Bb1 protein on adults. Impacts on NTOs caused by potential unintended changes in maize MON 88017 are not expected to occur, as no differences in composition, phenotypic characteristics and plant-NTO interactions were observed between maize MON 88017 and its near-isogenic line.

Original languageEnglish
Pages (from-to)1191-1214
Number of pages24
JournalTransgenic Research
Volume21
Issue number6
DOIs
Publication statusPublished - Dec 2012

Fingerprint

nontarget organisms
Zea mays
corn
Pollen
Chrysomelidae
adverse effects
pollen
rootworms
insecticidal proteins
Proteins
Beetles
isogenic lines
Larva
host plants
proteins
Coleoptera
larvae

Keywords

  • Adverse effects
  • Cry3Bb1
  • Environmental risk assessment
  • Genetically modified maize
  • Insect resistance
  • MON 863
  • MON 88017
  • Non-target organisms
  • Tiered approach

ASJC Scopus subject areas

  • Biotechnology
  • Genetics
  • Agronomy and Crop Science
  • Animal Science and Zoology

Cite this

Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms. / Devos, Yann; de Schrijver, Adinda; de Clercq, Patrick; Kiss, J.; Romeis, Jörg.

In: Transgenic Research, Vol. 21, No. 6, 12.2012, p. 1191-1214.

Research output: Contribution to journalArticle

Devos, Yann ; de Schrijver, Adinda ; de Clercq, Patrick ; Kiss, J. ; Romeis, Jörg. / Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms. In: Transgenic Research. 2012 ; Vol. 21, No. 6. pp. 1191-1214.
@article{5f52d494638440cea02459370204eae7,
title = "Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms",
abstract = "This review paper explores whether the cultivation of the genetically modified Bt-maize transformation event MON 88017, expressing the insecticidal Cry3Bb1 protein against corn rootworms (Coleoptera: Chrysomelidae), causes adverse effects to non-target organisms (NTOs) and the ecological and anthropocentric functions they provide. Available data do not reveal adverse effects of Cry3Bb1 on various NTOs that are representative of potentially exposed taxonomic and functional groups, confirming that the insecticidal activity of the Cry3Bb1 protein is limited to species belonging to the coleopteran family of Chrysomelidae. The potential risk to non-target chrysomelid larvae ingesting maize MON 88017 pollen deposited on host plants is minimal, as their abundance in maize fields and the likelihood of encountering harmful amounts of pollen in and around maize MON 88017 fields are low. Non-target adult chrysomelids, which may occasionally feed on maize MON 88017 plants, are not expected to be affected due to the low activity of the Cry3Bb1 protein on adults. Impacts on NTOs caused by potential unintended changes in maize MON 88017 are not expected to occur, as no differences in composition, phenotypic characteristics and plant-NTO interactions were observed between maize MON 88017 and its near-isogenic line.",
keywords = "Adverse effects, Cry3Bb1, Environmental risk assessment, Genetically modified maize, Insect resistance, MON 863, MON 88017, Non-target organisms, Tiered approach",
author = "Yann Devos and {de Schrijver}, Adinda and {de Clercq}, Patrick and J. Kiss and J{\"o}rg Romeis",
year = "2012",
month = "12",
doi = "10.1007/s11248-012-9617-z",
language = "English",
volume = "21",
pages = "1191--1214",
journal = "Transgenic Research",
issn = "0962-8819",
publisher = "Springer Netherlands",
number = "6",

}

TY - JOUR

T1 - Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms

AU - Devos, Yann

AU - de Schrijver, Adinda

AU - de Clercq, Patrick

AU - Kiss, J.

AU - Romeis, Jörg

PY - 2012/12

Y1 - 2012/12

N2 - This review paper explores whether the cultivation of the genetically modified Bt-maize transformation event MON 88017, expressing the insecticidal Cry3Bb1 protein against corn rootworms (Coleoptera: Chrysomelidae), causes adverse effects to non-target organisms (NTOs) and the ecological and anthropocentric functions they provide. Available data do not reveal adverse effects of Cry3Bb1 on various NTOs that are representative of potentially exposed taxonomic and functional groups, confirming that the insecticidal activity of the Cry3Bb1 protein is limited to species belonging to the coleopteran family of Chrysomelidae. The potential risk to non-target chrysomelid larvae ingesting maize MON 88017 pollen deposited on host plants is minimal, as their abundance in maize fields and the likelihood of encountering harmful amounts of pollen in and around maize MON 88017 fields are low. Non-target adult chrysomelids, which may occasionally feed on maize MON 88017 plants, are not expected to be affected due to the low activity of the Cry3Bb1 protein on adults. Impacts on NTOs caused by potential unintended changes in maize MON 88017 are not expected to occur, as no differences in composition, phenotypic characteristics and plant-NTO interactions were observed between maize MON 88017 and its near-isogenic line.

AB - This review paper explores whether the cultivation of the genetically modified Bt-maize transformation event MON 88017, expressing the insecticidal Cry3Bb1 protein against corn rootworms (Coleoptera: Chrysomelidae), causes adverse effects to non-target organisms (NTOs) and the ecological and anthropocentric functions they provide. Available data do not reveal adverse effects of Cry3Bb1 on various NTOs that are representative of potentially exposed taxonomic and functional groups, confirming that the insecticidal activity of the Cry3Bb1 protein is limited to species belonging to the coleopteran family of Chrysomelidae. The potential risk to non-target chrysomelid larvae ingesting maize MON 88017 pollen deposited on host plants is minimal, as their abundance in maize fields and the likelihood of encountering harmful amounts of pollen in and around maize MON 88017 fields are low. Non-target adult chrysomelids, which may occasionally feed on maize MON 88017 plants, are not expected to be affected due to the low activity of the Cry3Bb1 protein on adults. Impacts on NTOs caused by potential unintended changes in maize MON 88017 are not expected to occur, as no differences in composition, phenotypic characteristics and plant-NTO interactions were observed between maize MON 88017 and its near-isogenic line.

KW - Adverse effects

KW - Cry3Bb1

KW - Environmental risk assessment

KW - Genetically modified maize

KW - Insect resistance

KW - MON 863

KW - MON 88017

KW - Non-target organisms

KW - Tiered approach

UR - http://www.scopus.com/inward/record.url?scp=84870334890&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870334890&partnerID=8YFLogxK

U2 - 10.1007/s11248-012-9617-z

DO - 10.1007/s11248-012-9617-z

M3 - Article

VL - 21

SP - 1191

EP - 1214

JO - Transgenic Research

JF - Transgenic Research

SN - 0962-8819

IS - 6

ER -