Breeding of a distiller's yeast by hybridization with a wine yeast

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Hybrids were constructed between auxotrophic mutants of a heterothallic distiller's strain and a homothallic wine yeast. The hybridization resulted in a significant increase in both ethanol production and tolerance against exogenous ethanol. The hybrids were heterogeneous in ploidy, probably due to segregation of aneuploids during culturing. Sporulation of the hybrids broke down the high productivity, producing spore clones that were mostly of various intermediate levels of performance. However, a meiotic product superior to both crossing partners was also found. The results demonstrate that fermentation capacity can be improved by crossing with a low performance strain.

Original languageEnglish
Pages (from-to)638-642
Number of pages5
JournalApplied Microbiology and Biotechnology
Issue number5
Publication statusPublished - Aug 1 1991


ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

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