Breeding for scrapie resistance in the Hungarian sheep population

László Fésüs, Attila Zsolnai, István Anton, László Sáfár

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The first results of the Hungarian sheep prion protein (PrP) genotyping programme are discussed in this paper. To obtain initial genotype frequency data 10 commercial (Hungarian Merino, German Mutton Merino, Merino Landschaf, German Blackheaded, Suffolk, Texel, Ile de France, Charollais, Lacaune, British Milksheep) and 4 indigenous (Gyimes Racka, Hortobágy Racka, Tsigaja, Cikta) breeds were sampled in 2003 and 2004, and the PrP genotypes were determined by microsequencing analysis with capillary electrophoresis. In all commercial breeds, a higher number of sheep were genotyped in 2005 (3648) and in 2006 (3834) within the breeding programme to increase scrapie resistance, and the estimated frequency data were compared to the initial figures to evaluate the efficiency of selection. The new developments arising from the identification of the so-called 'atypical' scrapie cases are also discussed.

Original languageEnglish
Pages (from-to)173-180
Number of pages8
JournalActa veterinaria Hungarica
Volume56
Issue number2
DOIs
Publication statusPublished - Oct 1 2008

Keywords

  • Marker-assisted selection
  • Prion protein genotypes
  • Scrapie
  • Sheep

ASJC Scopus subject areas

  • veterinary(all)

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