Breeding for scrapie resistance in the Hungarian sheep population

László Fésüs, A. Zsolnai, István Anton, László Sáfár

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The first results of the Hungarian sheep prion protein (PrP) genotyping programme are discussed in this paper. To obtain initial genotype frequency data 10 commercial (Hungarian Merino, German Mutton Merino, Merino Landschaf, German Blackheaded, Suffolk, Texel, Ile de France, Charollais, Lacaune, British Milksheep) and 4 indigenous (Gyimes Racka, Hortobágy Racka, Tsigaja, Cikta) breeds were sampled in 2003 and 2004, and the PrP genotypes were determined by microsequencing analysis with capillary electrophoresis. In all commercial breeds, a higher number of sheep were genotyped in 2005 (3648) and in 2006 (3834) within the breeding programme to increase scrapie resistance, and the estimated frequency data were compared to the initial figures to evaluate the efficiency of selection. The new developments arising from the identification of the so-called 'atypical' scrapie cases are also discussed.

Original languageEnglish
Pages (from-to)173-180
Number of pages8
JournalActa Veterinaria Hungarica
Volume56
Issue number2
DOIs
Publication statusPublished - 2008

Fingerprint

Scrapie
scrapie
prions
Breeding
Sheep
Genotype
breeds
Suffolk (sheep breed)
sheep
Texel
mutton
genotype
capillary electrophoresis
breeding
Capillary Electrophoresis
Merino
genotyping
Population
France
Prion Proteins

Keywords

  • Marker-assisted selection
  • Prion protein genotypes
  • Scrapie
  • Sheep

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Breeding for scrapie resistance in the Hungarian sheep population. / Fésüs, László; Zsolnai, A.; Anton, István; Sáfár, László.

In: Acta Veterinaria Hungarica, Vol. 56, No. 2, 2008, p. 173-180.

Research output: Contribution to journalArticle

Fésüs, László ; Zsolnai, A. ; Anton, István ; Sáfár, László. / Breeding for scrapie resistance in the Hungarian sheep population. In: Acta Veterinaria Hungarica. 2008 ; Vol. 56, No. 2. pp. 173-180.
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