Branching-pattern analysis of the dendritic arborization in the thalamic nuclei of the rat brain

Cs Szigeti, Z. Fülöp, K. Gulya

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We investigated the dendritic patterns of rapid Golgi-impregnated, highly similar multipolar neurons from two functionally different thalamic regions of the rat brain: two dorsal nuclei (the nucleus laterodorsalis thalami, pars dorsomedialis and the nucleus laterodorsalis thalami, pars ventrolateralis), and two ventral nuclei (the nucleus ventrolateralis thalami and the nucleus ventromedialis thalami). The analysis involved conventional morphometric parameters (height and size) and a new parameter derived from graph theory, the relative imbalance (RI), derived from the branching patterns of the dendrites, which permits quantitative characterization of the dendritic arborization of a neuron. On this basis, neurons can be grouped into three fundamentally different types: type A, or highly-polarized (imbalanced) neurons (RI values close to I); type B, or medium-polarized neurons (RI values around 0.5); and type C, or balanced neurons with low polarization (RI values close to 0). The orientations of the dendritic arbor, and thus the receptive fields, of the dorsal and ventral thalamic neurons, were mutually perpendicular. The H and S values indicated that the neurons in the dorsal and ventral thalamic nuclei differed significantly. However, their RI values demonstrated that they were similar neurons of type B. Our data reveal that 1) the dendritic arbor cannot be reliably characterized purely on the basis of height and size, and 2) RI is a valuable morphometric parameter that identifies the true nature of the dendritic arborization.

Original languageEnglish
Pages (from-to)177-186
Number of pages10
JournalActa Biologica Hungarica
Volume53
Issue number1-2
DOIs
Publication statusPublished - 2002

Fingerprint

Thalamic Nuclei
Neuronal Plasticity
Neurons
branching
brain
Rats
Brain
neurons
rats
thalamus
Ventral Thalamic Nuclei
polarization
Thalamus
Mediodorsal Thalamic Nucleus
parameter
analysis
dendrites
Graph theory
Dendrites
Polarization

Keywords

  • Dendritic arborization
  • Golgi impregnation
  • Morphometry
  • Rat
  • Relative imbalance
  • Thalamus

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Branching-pattern analysis of the dendritic arborization in the thalamic nuclei of the rat brain. / Szigeti, Cs; Fülöp, Z.; Gulya, K.

In: Acta Biologica Hungarica, Vol. 53, No. 1-2, 2002, p. 177-186.

Research output: Contribution to journalArticle

@article{0b65a47616c944e8bfcfddee5bc4710f,
title = "Branching-pattern analysis of the dendritic arborization in the thalamic nuclei of the rat brain",
abstract = "We investigated the dendritic patterns of rapid Golgi-impregnated, highly similar multipolar neurons from two functionally different thalamic regions of the rat brain: two dorsal nuclei (the nucleus laterodorsalis thalami, pars dorsomedialis and the nucleus laterodorsalis thalami, pars ventrolateralis), and two ventral nuclei (the nucleus ventrolateralis thalami and the nucleus ventromedialis thalami). The analysis involved conventional morphometric parameters (height and size) and a new parameter derived from graph theory, the relative imbalance (RI), derived from the branching patterns of the dendrites, which permits quantitative characterization of the dendritic arborization of a neuron. On this basis, neurons can be grouped into three fundamentally different types: type A, or highly-polarized (imbalanced) neurons (RI values close to I); type B, or medium-polarized neurons (RI values around 0.5); and type C, or balanced neurons with low polarization (RI values close to 0). The orientations of the dendritic arbor, and thus the receptive fields, of the dorsal and ventral thalamic neurons, were mutually perpendicular. The H and S values indicated that the neurons in the dorsal and ventral thalamic nuclei differed significantly. However, their RI values demonstrated that they were similar neurons of type B. Our data reveal that 1) the dendritic arbor cannot be reliably characterized purely on the basis of height and size, and 2) RI is a valuable morphometric parameter that identifies the true nature of the dendritic arborization.",
keywords = "Dendritic arborization, Golgi impregnation, Morphometry, Rat, Relative imbalance, Thalamus",
author = "Cs Szigeti and Z. F{\"u}l{\"o}p and K. Gulya",
year = "2002",
doi = "10.1556/ABiol.53.2002.1-2.17",
language = "English",
volume = "53",
pages = "177--186",
journal = "Acta Biologica Hungarica",
issn = "0236-5383",
publisher = "Akademiai Kiado",
number = "1-2",

}

TY - JOUR

T1 - Branching-pattern analysis of the dendritic arborization in the thalamic nuclei of the rat brain

AU - Szigeti, Cs

AU - Fülöp, Z.

AU - Gulya, K.

PY - 2002

Y1 - 2002

N2 - We investigated the dendritic patterns of rapid Golgi-impregnated, highly similar multipolar neurons from two functionally different thalamic regions of the rat brain: two dorsal nuclei (the nucleus laterodorsalis thalami, pars dorsomedialis and the nucleus laterodorsalis thalami, pars ventrolateralis), and two ventral nuclei (the nucleus ventrolateralis thalami and the nucleus ventromedialis thalami). The analysis involved conventional morphometric parameters (height and size) and a new parameter derived from graph theory, the relative imbalance (RI), derived from the branching patterns of the dendrites, which permits quantitative characterization of the dendritic arborization of a neuron. On this basis, neurons can be grouped into three fundamentally different types: type A, or highly-polarized (imbalanced) neurons (RI values close to I); type B, or medium-polarized neurons (RI values around 0.5); and type C, or balanced neurons with low polarization (RI values close to 0). The orientations of the dendritic arbor, and thus the receptive fields, of the dorsal and ventral thalamic neurons, were mutually perpendicular. The H and S values indicated that the neurons in the dorsal and ventral thalamic nuclei differed significantly. However, their RI values demonstrated that they were similar neurons of type B. Our data reveal that 1) the dendritic arbor cannot be reliably characterized purely on the basis of height and size, and 2) RI is a valuable morphometric parameter that identifies the true nature of the dendritic arborization.

AB - We investigated the dendritic patterns of rapid Golgi-impregnated, highly similar multipolar neurons from two functionally different thalamic regions of the rat brain: two dorsal nuclei (the nucleus laterodorsalis thalami, pars dorsomedialis and the nucleus laterodorsalis thalami, pars ventrolateralis), and two ventral nuclei (the nucleus ventrolateralis thalami and the nucleus ventromedialis thalami). The analysis involved conventional morphometric parameters (height and size) and a new parameter derived from graph theory, the relative imbalance (RI), derived from the branching patterns of the dendrites, which permits quantitative characterization of the dendritic arborization of a neuron. On this basis, neurons can be grouped into three fundamentally different types: type A, or highly-polarized (imbalanced) neurons (RI values close to I); type B, or medium-polarized neurons (RI values around 0.5); and type C, or balanced neurons with low polarization (RI values close to 0). The orientations of the dendritic arbor, and thus the receptive fields, of the dorsal and ventral thalamic neurons, were mutually perpendicular. The H and S values indicated that the neurons in the dorsal and ventral thalamic nuclei differed significantly. However, their RI values demonstrated that they were similar neurons of type B. Our data reveal that 1) the dendritic arbor cannot be reliably characterized purely on the basis of height and size, and 2) RI is a valuable morphometric parameter that identifies the true nature of the dendritic arborization.

KW - Dendritic arborization

KW - Golgi impregnation

KW - Morphometry

KW - Rat

KW - Relative imbalance

KW - Thalamus

UR - http://www.scopus.com/inward/record.url?scp=0036010812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036010812&partnerID=8YFLogxK

U2 - 10.1556/ABiol.53.2002.1-2.17

DO - 10.1556/ABiol.53.2002.1-2.17

M3 - Article

C2 - 12064770

AN - SCOPUS:0036010812

VL - 53

SP - 177

EP - 186

JO - Acta Biologica Hungarica

JF - Acta Biologica Hungarica

SN - 0236-5383

IS - 1-2

ER -