Brain-specific expression of transthyretin mRNA as revealed by cDNA cloning from brain

Kiyoto Motojima, Sataro Goto

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

cDNAs for rat transthyretin mRNA were cloned from a brain cDNA library. Sequencing analyses showed the presence of an additional 5' sequence that had not been reported for the liver mRNA corresponding to the flanking promoter region of the gene. This additional sequence was expressed only in the brain, suggesting the presence of a brain-specific promoter.

Original languageEnglish
Pages (from-to)103-105
Number of pages3
JournalFEBS letters
Volume258
Issue number1
DOIs
Publication statusPublished - Nov 20 1989

Keywords

  • (Rat brain)
  • Alternative promoter
  • Brain-specific expression
  • Nucleotide sequence
  • Prealbumin
  • Transthyretin

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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