Brain responses to passive sensory stimulation correlate with intelligence

Anna Horwitz, Marc Klemp, Henrik Horwitz, Mia Dyhr Thomsen, Egill Rostrup, Erik Lykke Mortensen, Merete Osler, Martin Lauritzen, K. Benedek

Research output: Contribution to journalArticle

Abstract

This study investigates the association between intelligence and brain power responses to a passive audiovisual stimulation. We measure the power of gamma-range steady-state responses (SSRs) as well as intelligence and other aspects of neurocognitive function in 40 healthy males born in 1953. The participants are a part of a Danish birth cohort study and the data therefore include additional information measured earlier in life. Our main power measure is the difference in power between a visual stimulation and a combined audiovisual stimulation. We hypothesize and establish empirically that the power measure is associated with intelligence. In particular, we find a highly significant correlation between the power measure and present intelligence scores. The association is robust to controlling for size-at-birth measures, length of education, speed of processing as well as a range of other potentially confounding factors. Interestingly, we find that intelligence scores measured earlier in life (childhood, youth, late midlife), are also correlated with the present-day power measure, suggesting a deep connection between intelligence and the power measure. Finally, we find that the power measure has a high sensitivity for detection of an intelligence score below the average. HIGHLIGHTS - Intelligence scores are correlated with the change in steady-state evoked power responses from single to double-sensory stimulation (1P). - Intelligence scores measured earlier in life (childhood, youth, and late midlife), in addition to scores measured presently in old age, are also associated with present-day 1P. - The correlations are not driven by observed covariates, including birth size, education, processing speed, or a range of other potentially confounding factors determined after youth, nor other day-specific factors or factors that operate in an additive and constant fashion on the level of steady-state power responses.

Original languageEnglish
Article number201
JournalFrontiers in Aging Neuroscience
Volume10
Issue numberJUL
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Intelligence
Brain
Parturition
Power (Psychology)
Education
Photic Stimulation
Cohort Studies

Keywords

  • Aging
  • EEG
  • Gamma power
  • Intelligence
  • Longitudinal intelligence scores
  • Neurocognitive function
  • Steady-state evoked potentials

ASJC Scopus subject areas

  • Ageing
  • Cognitive Neuroscience

Cite this

Horwitz, A., Klemp, M., Horwitz, H., Thomsen, M. D., Rostrup, E., Mortensen, E. L., ... Benedek, K. (2019). Brain responses to passive sensory stimulation correlate with intelligence. Frontiers in Aging Neuroscience, 10(JUL), [201]. https://doi.org/10.3389/fnagi.2019.00201

Brain responses to passive sensory stimulation correlate with intelligence. / Horwitz, Anna; Klemp, Marc; Horwitz, Henrik; Thomsen, Mia Dyhr; Rostrup, Egill; Mortensen, Erik Lykke; Osler, Merete; Lauritzen, Martin; Benedek, K.

In: Frontiers in Aging Neuroscience, Vol. 10, No. JUL, 201, 01.01.2019.

Research output: Contribution to journalArticle

Horwitz, A, Klemp, M, Horwitz, H, Thomsen, MD, Rostrup, E, Mortensen, EL, Osler, M, Lauritzen, M & Benedek, K 2019, 'Brain responses to passive sensory stimulation correlate with intelligence', Frontiers in Aging Neuroscience, vol. 10, no. JUL, 201. https://doi.org/10.3389/fnagi.2019.00201
Horwitz A, Klemp M, Horwitz H, Thomsen MD, Rostrup E, Mortensen EL et al. Brain responses to passive sensory stimulation correlate with intelligence. Frontiers in Aging Neuroscience. 2019 Jan 1;10(JUL). 201. https://doi.org/10.3389/fnagi.2019.00201
Horwitz, Anna ; Klemp, Marc ; Horwitz, Henrik ; Thomsen, Mia Dyhr ; Rostrup, Egill ; Mortensen, Erik Lykke ; Osler, Merete ; Lauritzen, Martin ; Benedek, K. / Brain responses to passive sensory stimulation correlate with intelligence. In: Frontiers in Aging Neuroscience. 2019 ; Vol. 10, No. JUL.
@article{b3d794fbb2a84c2f92c1763f8ec855b7,
title = "Brain responses to passive sensory stimulation correlate with intelligence",
abstract = "This study investigates the association between intelligence and brain power responses to a passive audiovisual stimulation. We measure the power of gamma-range steady-state responses (SSRs) as well as intelligence and other aspects of neurocognitive function in 40 healthy males born in 1953. The participants are a part of a Danish birth cohort study and the data therefore include additional information measured earlier in life. Our main power measure is the difference in power between a visual stimulation and a combined audiovisual stimulation. We hypothesize and establish empirically that the power measure is associated with intelligence. In particular, we find a highly significant correlation between the power measure and present intelligence scores. The association is robust to controlling for size-at-birth measures, length of education, speed of processing as well as a range of other potentially confounding factors. Interestingly, we find that intelligence scores measured earlier in life (childhood, youth, late midlife), are also correlated with the present-day power measure, suggesting a deep connection between intelligence and the power measure. Finally, we find that the power measure has a high sensitivity for detection of an intelligence score below the average. HIGHLIGHTS - Intelligence scores are correlated with the change in steady-state evoked power responses from single to double-sensory stimulation (1P). - Intelligence scores measured earlier in life (childhood, youth, and late midlife), in addition to scores measured presently in old age, are also associated with present-day 1P. - The correlations are not driven by observed covariates, including birth size, education, processing speed, or a range of other potentially confounding factors determined after youth, nor other day-specific factors or factors that operate in an additive and constant fashion on the level of steady-state power responses.",
keywords = "Aging, EEG, Gamma power, Intelligence, Longitudinal intelligence scores, Neurocognitive function, Steady-state evoked potentials",
author = "Anna Horwitz and Marc Klemp and Henrik Horwitz and Thomsen, {Mia Dyhr} and Egill Rostrup and Mortensen, {Erik Lykke} and Merete Osler and Martin Lauritzen and K. Benedek",
year = "2019",
month = "1",
day = "1",
doi = "10.3389/fnagi.2019.00201",
language = "English",
volume = "10",
journal = "Frontiers in Aging Neuroscience",
issn = "1663-4365",
publisher = "Frontiers Research Foundation",
number = "JUL",

}

TY - JOUR

T1 - Brain responses to passive sensory stimulation correlate with intelligence

AU - Horwitz, Anna

AU - Klemp, Marc

AU - Horwitz, Henrik

AU - Thomsen, Mia Dyhr

AU - Rostrup, Egill

AU - Mortensen, Erik Lykke

AU - Osler, Merete

AU - Lauritzen, Martin

AU - Benedek, K.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - This study investigates the association between intelligence and brain power responses to a passive audiovisual stimulation. We measure the power of gamma-range steady-state responses (SSRs) as well as intelligence and other aspects of neurocognitive function in 40 healthy males born in 1953. The participants are a part of a Danish birth cohort study and the data therefore include additional information measured earlier in life. Our main power measure is the difference in power between a visual stimulation and a combined audiovisual stimulation. We hypothesize and establish empirically that the power measure is associated with intelligence. In particular, we find a highly significant correlation between the power measure and present intelligence scores. The association is robust to controlling for size-at-birth measures, length of education, speed of processing as well as a range of other potentially confounding factors. Interestingly, we find that intelligence scores measured earlier in life (childhood, youth, late midlife), are also correlated with the present-day power measure, suggesting a deep connection between intelligence and the power measure. Finally, we find that the power measure has a high sensitivity for detection of an intelligence score below the average. HIGHLIGHTS - Intelligence scores are correlated with the change in steady-state evoked power responses from single to double-sensory stimulation (1P). - Intelligence scores measured earlier in life (childhood, youth, and late midlife), in addition to scores measured presently in old age, are also associated with present-day 1P. - The correlations are not driven by observed covariates, including birth size, education, processing speed, or a range of other potentially confounding factors determined after youth, nor other day-specific factors or factors that operate in an additive and constant fashion on the level of steady-state power responses.

AB - This study investigates the association between intelligence and brain power responses to a passive audiovisual stimulation. We measure the power of gamma-range steady-state responses (SSRs) as well as intelligence and other aspects of neurocognitive function in 40 healthy males born in 1953. The participants are a part of a Danish birth cohort study and the data therefore include additional information measured earlier in life. Our main power measure is the difference in power between a visual stimulation and a combined audiovisual stimulation. We hypothesize and establish empirically that the power measure is associated with intelligence. In particular, we find a highly significant correlation between the power measure and present intelligence scores. The association is robust to controlling for size-at-birth measures, length of education, speed of processing as well as a range of other potentially confounding factors. Interestingly, we find that intelligence scores measured earlier in life (childhood, youth, late midlife), are also correlated with the present-day power measure, suggesting a deep connection between intelligence and the power measure. Finally, we find that the power measure has a high sensitivity for detection of an intelligence score below the average. HIGHLIGHTS - Intelligence scores are correlated with the change in steady-state evoked power responses from single to double-sensory stimulation (1P). - Intelligence scores measured earlier in life (childhood, youth, and late midlife), in addition to scores measured presently in old age, are also associated with present-day 1P. - The correlations are not driven by observed covariates, including birth size, education, processing speed, or a range of other potentially confounding factors determined after youth, nor other day-specific factors or factors that operate in an additive and constant fashion on the level of steady-state power responses.

KW - Aging

KW - EEG

KW - Gamma power

KW - Intelligence

KW - Longitudinal intelligence scores

KW - Neurocognitive function

KW - Steady-state evoked potentials

UR - http://www.scopus.com/inward/record.url?scp=85071544099&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071544099&partnerID=8YFLogxK

U2 - 10.3389/fnagi.2019.00201

DO - 10.3389/fnagi.2019.00201

M3 - Article

AN - SCOPUS:85071544099

VL - 10

JO - Frontiers in Aging Neuroscience

JF - Frontiers in Aging Neuroscience

SN - 1663-4365

IS - JUL

M1 - 201

ER -