A tumorágy egyedüli brachyterápiája emlömegtartó mütét után: új sugárterápiás lehetöség a korai emlörák kezelésében.

Translated title of the contribution: Brachytherapy of the tumor bed after breast conserving surgery: new radiotherapeutic option in the management of early breast cancer

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

PURPOSE: To initiate fractionated, interstitial high dose rate brachytherapy of the tumour bed as the sole radiation modality after breast conserving surgery. PATIENTS AND METHODS: In 41 cases of selected stage I-II breast cancer the tumour bed was marked with titanium clips during breast conserving surgery. The tumour bed was implanted with flexible plastic catheters to deliver postoperative radiotherapy. In 8 cases 7 x 4.33 Gy (30.3 Gy), in 33 cases 7 x 5.2 Gy (36.4 Gy) interstitial 192Ir high dose rate brachytherapy was given to the clipped area. Irradiation of the whole conserved breast was omitted. The radiation side effects were assessed by mammograms and MRI-examinations. RESULTS: At a median follow up of 17 (4-36) months neither distant nor regional failure was observed. Local recurrence was detected in 1/41 (2.4%) case. G2 radiation side effects were observed in 2/21 (9.5%). CONCLUSIONS: Postoperative sole brachytherapy of the tumour bed with careful patient selection and adequate quality assurance seems to be a feasible alternative to whole breast teletherapy. Sole brachytherapy shortens the time of radiotherapy from 5-6 weeks to 5 days, and reduces the costs of treatment. The skin and volume sparing effect of interstitial irradiation may decrease the side effects of radiotherapy.

Translated title of the contributionBrachytherapy of the tumor bed after breast conserving surgery: new radiotherapeutic option in the management of early breast cancer
Original languageHungarian
Pages (from-to)1461-1466
Number of pages6
JournalOrvosi hetilap
Volume140
Issue number26
Publication statusPublished - Jun 27 1999

ASJC Scopus subject areas

  • Medicine(all)

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