A szarvasmarha vírusos hasmenése

Translated title of the contribution: Bovine viral diarrhoea

S. Kecskeméti, Kiss István

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The infection caused by bovine viral diarrhoea virus (BVDV) usually causes mild clinical symptoms in immunocompetent cattle. When infecting pregnant animals, the virus may invade the fetus, causing different pathological changes that largely depend on the affected period of gestation. In the first month of pregnancy, BVDV infection results in early embryonic death, return to heat, and abortion. Infection of the fetus by a non-cythopathogenic strain of BVDV between the 40th and 120th days of pregnancy leads to the delivery of persistently infected, immunotolerant animals that are persistently viraemic and can shed the virus during their whole lifetime. Infection between the 90th and 150th days of pregnancy may produce disorders of the central nervous system and the eyes. In the second half of pregnancy the fetus is able to produce antibodies against the virus. Bulls shed the virus via semen; in case of acute infection with lower titers and for a shorter period, while in case of persistent infections constantly and with a higher titer. Additionally, infection by BVDV exerts a remarkable suppression on the immune system of the host. There have been reports of haemorrhagic syndromes accompanied by thrombocytopenia, anaemia, haemorrhages, and severe mortality caused by BVDV. Mucosal disease (MD) may develop in animals persistently infected with a non-cythopathogenic BVDV by the superinfection of a cythopathogenic BVDV later on. When the superinfecting virus has a homologous antigenic structure, MD develops within two or three weeks resulting in high mortality. If the superinfecting virus is partially heterologous, a humoral immune response can be detected against it and the virus disappears from the blood, with MD developing weeks or months later. MD does not develop after a superinfection with heterologous cythopathogenic BVDV but rather antibodies are produced against the heterologous virus. Diagnosis of the diseases caused by BVDV is based on the clinical symptoms, pathological and histological alterations and results of laboratory investigations (demonstration of the presence of the virus, virus antigen or nucleic acid). Control of BVDV infection is based on the one hand on the prevention of introduction of the virus and on the other hand, on detection and elimination of persistently infected animals, prevention of transient and persistent Infections by vaccination and hygienic measures, as well as on the prevention of the enrichment of the causative agent on the farm.

Original languageHungarian
Pages (from-to)344-348
Number of pages5
JournalMagyar Allatorvosok Lapja
Volume121
Issue number6
Publication statusPublished - 1999

Fingerprint

Bovine Viral Diarrhea Viruses
bovine viral diarrhea
Bovine viral diarrhea virus
Diarrhea
Viruses
viruses
infection
Infection
pregnancy
Pregnancy
fetus
Superinfection
Fetus
Virus Diseases
signs and symptoms (animals and humans)
animals
abortion (animals)
antibodies
gestation period
thrombocytopenia

ASJC Scopus subject areas

  • veterinary(all)

Cite this

A szarvasmarha vírusos hasmenése. / Kecskeméti, S.; István, Kiss.

In: Magyar Allatorvosok Lapja, Vol. 121, No. 6, 1999, p. 344-348.

Research output: Contribution to journalArticle

Kecskeméti, S & István, K 1999, 'A szarvasmarha vírusos hasmenése', Magyar Allatorvosok Lapja, vol. 121, no. 6, pp. 344-348.
Kecskeméti, S. ; István, Kiss. / A szarvasmarha vírusos hasmenése. In: Magyar Allatorvosok Lapja. 1999 ; Vol. 121, No. 6. pp. 344-348.
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