Bovine herpesvirus type 4: A special herpesvirus (review article)

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

This paper summarizes the history of and information on bovine herpesvirus type 4 (BoHV-4) from the first isolation to the most recent results. For almost twenty years BoHV-4 has been considered a typical herpes 'orphan' virus, which infects several species but causes no illness. The latest experiments revealed the close relationship of this virus with the immune system and other tissues. The virus was even considered as a possible candidate for a vector vaccine. BoHV-4 as a strange herpesvirus has several features which are not characteristic of other herpesviruses, such as several latency sites, persistence in serum, dividing cells necessary for virus replication, and the wide host range. In addition to describing the main features of the virion, replication, clinical signs, nomenclature problems, this review intends to concentrate on the new and strange results coming out from several laboratories worldwide. It is also suggested that because the virus combines several properties of various herpesvirus subfamilies and because of its close relationship with the immune system, it may deserve further attention as a representative of a potentially new genus within the Gammaherpesvirinae subfamily.

Original languageEnglish
Pages (from-to)501-513
Number of pages13
JournalActa Veterinaria Hungarica
Volume48
Issue number4
Publication statusPublished - 2000

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Bovine Herpesvirus 4
Bovine herpesvirus 4
Herpesviridae
Viruses
viruses
immune system
Gammaherpesvirinae
Immune System
vector vaccines
Host Specificity
Virus Replication
virus replication
virion
Terminology
host range
Virion
new genus
Vaccines
concentrates
History

Keywords

  • Bovine herpesvirus type 4
  • Latency
  • Pathogenesis
  • Replication
  • Structure

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Bovine herpesvirus type 4 : A special herpesvirus (review article). / Egyed, L.

In: Acta Veterinaria Hungarica, Vol. 48, No. 4, 2000, p. 501-513.

Research output: Contribution to journalArticle

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