Bone‐scintigraphic examinations in patients treated with retinoids: a prospective study

L. TÖRÖK, L. Galuska, M. KÁSA, L. KÁDÁR

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13 Citations (Scopus)

Abstract

Possible early side‐effects of retinoid treatment on bones were studied with the aid of bone‐scintigraphy. Isotretinoin treatment (1.0 mg/kg daily for 4 months) was given to 18 patients with acne. Fifteen patients with psoriasis received etretinate treatment (0.7–1.0 mg/kg/day) for 4 months. In the group treated with isotretinoin, pathological uptake of radiolabel was found in three cases, while in the group treated with etretinate, no bone changes attributable to treatment were found. During isotretinoin treatment, a decrease in growth‐plate activity was observed. Bone‐scintigraphy is considered to be a suitable method for early screening for bone changes occurring in retinoid treatment.

Original languageEnglish
Pages (from-to)31-36
Number of pages6
JournalBritish Journal of Dermatology
Volume120
Issue number1
DOIs
Publication statusPublished - Jan 1 1989

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Retinoids
Prospective Studies
Isotretinoin
Etretinate
Bone and Bones
Therapeutics
Acne Vulgaris
Psoriasis

ASJC Scopus subject areas

  • Dermatology

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Bone‐scintigraphic examinations in patients treated with retinoids : a prospective study. / TÖRÖK, L.; Galuska, L.; KÁSA, M.; KÁDÁR, L.

In: British Journal of Dermatology, Vol. 120, No. 1, 01.01.1989, p. 31-36.

Research output: Contribution to journalArticle

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