Bone mineral density (BMD) and computer tomographic measurements of the equine proximal phalanx in correlation with breaking strength

P. Tóth, C. Horváth, V. Ferencz, B. Tóth, A. Váradi, O. Szenci, G. Bodó

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Despite the fact that bone mineral density (BMD) is an important fracture risk predictor in human medicine, studies in equine orthopedic research are still lacking. We hypothesized that BMD correlates with bone failure and fatigue fractures of this bone. Thus, the objectives of this study were to measure the structural and mechanical properties of the proximal phalanx with dual energy X-ray absorptiometry (DXA), to correlate the data obtained from DXA and computer tomography (CT) measurements to those obtained by loading pressure examination and to establish representative region of interest (ROI) for in vitro BMD measurements of the equine proximal phalanx for predicting bone failure force. DXA was used to measure the whole bone BMD and additional three ROI sites in 14 equine proximal phalanges. Following evaluation of the bone density, whole bone, cortical width and area in the mid-diaphyseal plane were measured on CT images. Bones were broken using a manually controlled universal bone crusher to measure bone failure force and reevaluated for the site of fractures on follow-up CT images. Compressive load was applied at a constant displacement rate of 2 mm/min until failure, defined as the first clear drop in the load measurement. The lowest BMD was measured at the trabecular region (mean ± SD: 1.52 ± 0.12 g/cm2; median: 1.48 g/cm2; range: 1.38-1.83 g/cm2). There was a significant positive linear correlation between trabelcular BMD and the breaking strength (P=0.023, r=0.62). The trabecular region of the proximal phalanx appears to be the only significant indicator of failure of strength in vitro. This finding should be reassessed to further reveal the prognostic value of trabecular BMD in an in vivo fracture risk model.

Original languageEnglish
Pages (from-to)3-8
Number of pages6
JournalPolish Journal of Veterinary Sciences
Volume16
Issue number1
DOIs
Publication statusPublished - Mar 2013

Fingerprint

phalanges
bone density
strength (mechanics)
Bone Density
Horses
bones
horses
dual-energy X-ray absorptiometry
tomography
Photon Absorptiometry
Bone and Bones
Bone Fractures
Tomography
crushers
stress fractures
Stress Fractures
orthopedics
mechanical properties
Orthopedics
medicine

Keywords

  • Bone mineral density
  • Breaking strength
  • CT
  • DXA
  • First phalanx
  • Horse

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Bone mineral density (BMD) and computer tomographic measurements of the equine proximal phalanx in correlation with breaking strength. / Tóth, P.; Horváth, C.; Ferencz, V.; Tóth, B.; Váradi, A.; Szenci, O.; Bodó, G.

In: Polish Journal of Veterinary Sciences, Vol. 16, No. 1, 03.2013, p. 3-8.

Research output: Contribution to journalArticle

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