Bone marrow (reticuloendothelial system) scintigraphy for haematological follow-up of radiochemotherapy-treated patients

Olga Ésik, Mária Rajtár, Attila Naszály

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

To assess the bone marrow capacity before a new treatment decision, 99mTc-human serum albumin bone marrow scintigraphy (with qualitative and quan-titative evaluation) was performed in 32 patients with solid tumours or malig-nant lymphomas previously treated with radiochemotherapy. In the group with a normal bone marrow capacity, the blood counts were normal (14/16 cases) or became normal (2/16 cases) in the follow-up period, and the examined marrow samples exhibited normal haemopoiesis. In the group with a reduced bone marrow capacity, one or more blood counts were low in 14/16 cases. Decreased haemopoiesis was observed in only 4 of 8 examined marrow samples. The following conclusions were drawn. (1) A scintigraphically normal bone marrow capacity relates to normal haematological parameters, and therefore treatment plans could be decided on. (2) Although a reduced bone marrow capacity indicates pathological haemotological conditions in the majority of cases, further studies are needed to evaluate its precise significance. (3) Application of this non-invasive, inexpensive, repeatable, non-immunizing method is recommended before a therapeutic plan is decided on for patients at consider-able haematological risk.

Original languageEnglish
Pages (from-to)298-302
Number of pages5
JournalOncology (Switzerland)
Volume50
Issue number4
DOIs
Publication statusPublished - Jan 1 1993

Keywords

  • Bone marrow capacity
  • Bone marrow scintigraphy
  • Radiochemotherapy
  • Tumour

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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