Bone-Albumin filling decreases donor site morbidity and enhances bone formation after anterior cruciate ligament reconstruction with bone-patellar tendon-bone autografts

Károly Schandl, Dénes B. Horváthy, Attila Doros, Ernő Majzik, Charlotte M. Schwarz, Lajos Csönge, Géza Abkarovits, László Bucsi, Z. Lacza

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: Donor site pain affects 32–43 % of patients after anterior cruciate ligament surgery when the autograft is freshly harvested bone-patellar tendon-bone tissue. Our aim was to compare functional and morphological differences between donor sites with and without serum albumin-coated bone allograft filling. Methods: After harvesting and implanting the graft, the tibia site was filled with either fresh autologous cancellous bone enhanced with albumin-coated allograft or autologous bone alone. The patella site was filled either with albumin-coated allograft or with blood clot. Knee function was evaluated by the VISA, Lysholm and IKDC scores and a visual analog scale of pain during standing, kneeling and crouching after six weeks and six months. Computed tomography was performed at six months for morphological evaluation. Results: At six weeks, both groups were still recovering from surgery and the overall knee function was still impaired but the functional scores were significantly higher in the Bone-Albumin group. The pain with crouching and kneeling was also lower as compared to controls. At six months, the knee function scores were close to normal, with a slight decrease in the controls. Pain at kneeling was still prominent in the controls, but significantly lower in the Bone-Albumin group. Computed tomography showed significantly smaller bone defects and higher bone density in the Bone-Albumin group. Conclusions: Results from the present study indicate that donor site pain, a disturbing long-term side effect of bone-patellar tendon-bone surgery, is significantly reduced if bone buildup in the patella and the tibia is augmented by serum albumin-coated bone allografts.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalInternational Orthopaedics
DOIs
Publication statusAccepted/In press - Jun 29 2016

Keywords

  • Albumin
  • Anterior cruciate ligament
  • Bone allograft
  • Bone-Albumin
  • Bone-tendon-bone
  • BTB
  • Serum

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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