Bombesin injection into the central amygdala influences feeding behavior in the rat

J. Vígh, L. Lénárd, É Fekete, I. Hernádi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The present study was performed to determine whether low doses (10 or 40 ng) of bombesin microinjected into the amygdala could modify solid food intake. Forty ng of bombesin in 24 h deprived rats caused transient inhibition of food intake. This inhibitory effect was eliminated by prior bombesin antagonist treatment. A series of quantitative behavioral tests indicated that low doses of bombesin application specifically reduced food intake without altering the behavioral pattern or influencing the body temperature. The present results suggest, that bombesin-like peptides may act as a satiety signal in the central part of the amygdala. Copyright (C) 1999 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)437-444
Number of pages8
JournalPeptides
Volume20
Issue number4
DOIs
Publication statusPublished - May 1999

Fingerprint

Bombesin
Feeding Behavior
Rats
Injections
Eating
Amygdala
Body Temperature
Central Amygdaloid Nucleus
Peptides

Keywords

  • Amygdala
  • Behavior
  • Body temperature
  • Bombesin
  • Feeding

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Physiology
  • Cellular and Molecular Neuroscience

Cite this

Bombesin injection into the central amygdala influences feeding behavior in the rat. / Vígh, J.; Lénárd, L.; Fekete, É; Hernádi, I.

In: Peptides, Vol. 20, No. 4, 05.1999, p. 437-444.

Research output: Contribution to journalArticle

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